(Z)-Sacubitril Maleic Acid

Name: (Z)-Sacubitril Maleic Acid
Brand: Vaqora Chemicals
SKU: VQ-021334

About (Z)-Sacubitril Maleic Acid

Vaqora Chemicals supplies (Z)-Sacubitril Maleic Acid, an impurity of Sacubitril registered under CAS number 2751722-77-5. Its molecular formula is C24H27NO5 and its molecular weight is 409.5 g/mol. Its systematic (IUPAC) name is (Z)-4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobut-2-enoic acid. It is also known as Sacubitril Maleic Acid (Z-Isomer) or (Z)2S,4R-Sacubitril.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Sacubitril, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (Z)-Sacubitril Maleic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	(Z)-Sacubitril Maleic Acid
Catalogue No.	VQ-021334
CAS Number	2751722-77-5
IUPAC name	(Z)-4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobut-2-enoic acid
Molecular formula	C₂₄H₂₇NO₅
Molecular weight	409.5 g/mol
Exact mass	409.1889
Grade	Reference Standard
HSN code	38229090
InChIKey	OBIKFELFUFDHLD-JLMIGJNSSA-N
SMILES	CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)/C=C\C(=O)O
PubChem CID	127255953

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	2 / 5
TPSA	92.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (Z)-Sacubitril Maleic Acid?

The CAS Registry Number of (Z)-Sacubitril Maleic Acid is 2751722-77-5. It is also known as Sacubitril Maleic Acid (Z-Isomer), (Z)2S,4R-Sacubitril, (E)-Sacubitril Maleic Acid.

What is the molecular formula and molecular weight of (Z)-Sacubitril Maleic Acid?

(Z)-Sacubitril Maleic Acid has the molecular formula C24H27NO5 and a molecular weight of 409.5 g/mol. Its IUPAC name is (Z)-4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobut-2-enoic acid.

What is (Z)-Sacubitril Maleic Acid used for?

(Z)-Sacubitril Maleic Acid is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (Z)-Sacubitril Maleic Acid can I order?

We supply (Z)-Sacubitril Maleic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (Z)-Sacubitril Maleic Acid?

Yes. Every lot of (Z)-Sacubitril Maleic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (Z)-Sacubitril Maleic Acid be shipped internationally?

Yes. We export (Z)-Sacubitril Maleic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.