1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glut… 2820151-35-5

About 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate

1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate is an impurity of Methotrexate carrying the CAS registry number 2820151-35-5. Its molecular formula is C17H24N2O5 and its molecular weight is 336.4 g/mol. Its systematic (IUPAC) name is diethyl (2S)-2-[[3-(methylamino)benzoyl]amino]pentanedioate. It is also known as Diethyl N-(3-Methylaminobenzoyl)-L-glutamate or Diethyl (3-(methylamino)benzoyl)-L-glutamate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Methotrexate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate
Catalogue No.	VQ-044722
CAS Number	2820151-35-5
IUPAC name	diethyl (2S)-2-[[3-(methylamino)benzoyl]amino]pentanedioate
Molecular formula	C₁₇H₂₄N₂O₅
Molecular weight	336.4 g/mol
Exact mass	336.1685
Grade	Reference Standard
HSN code	38229090
InChIKey	CSYABNNOSSRTQX-AWEZNQCLSA-N
SMILES	CCOC(=O)CC[C@@H](C(=O)OCC)NC(=O)C1=CC(=CC=C1)NC
PubChem CID	169437946

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 6
TPSA	93.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate?

The CAS Registry Number of 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate is 2820151-35-5. It is also known as Diethyl N-(3-Methylaminobenzoyl)-L-glutamate, Diethyl (3-(methylamino)benzoyl)-L-glutamate.

What is the molecular formula and molecular weight of 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate?

1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate has the molecular formula C17H24N2O5 and a molecular weight of 336.4 g/mol. Its IUPAC name is diethyl (2S)-2-[[3-(methylamino)benzoyl]amino]pentanedioate.

What is 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate used for?

1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate can I order?

We supply 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate?

Yes. Every lot of 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate be shipped internationally?

Yes. We export 1,5-Diethyl N-[3-(methylamino)benzoyl]-L-glutamate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.