Cinnarizine

About Cinnarizine

Cinnarizine is a central nervous system API (IP/BP/USP grade) carrying the CAS registry number 298-57-7. With the molecular formula C26H28N2, it has a molar mass of 368.5 g/mol. The IUPAC name is 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine. Common synonyms include Folcodal and Labyrin.

In its supplied form it is a white crystalline powder. Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our CNS and psychiatric APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Our customers for this product work in pharmaceutical manufacturing.

Standard pack sizes are 1 kg, 5 kg and 25 kg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Cinnarizine

View every impurity, metabolite and intermediate we list for Cinnarizine.

Cinnarizine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cinnarizine
Catalogue No.	VQ-004032
CAS Number	298-57-7
IUPAC name	1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
Molecular formula	C₂₆H₂₈N₂
Molecular weight	368.5 g/mol
Exact mass	368.2252
Grade	IP/BP/USP
HSN code	2933
InChIKey	DERZBLKQOCDDDZ-JLHYYAGUSA-N
SMILES	C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4
PubChem CID	1547484

Physical properties
Physical form	Powder
Appearance	White crystalline powder
LogP (XLogP3)	5.8
H-bond donors / acceptors	0 / 2
TPSA	6.5 Å²
Synonyms	Folcodal, Labyrin, Midronal, Mitronal, Stutgin, Cinarizine, Cinaperazine, Aplexal, Cinnipirine, Processine, Sedatromin, Spaderizine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H360May damage fertility or the unborn child
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P264, P273, P280, P302 + P352, P318, P321, P332 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cinnarizine?

The CAS Registry Number of Cinnarizine is 298-57-7. It is also known as Folcodal, Labyrin, Midronal.

What is the molecular formula and molecular weight of Cinnarizine?

Cinnarizine has the molecular formula C26H28N2 and a molecular weight of 368.5 g/mol. Its IUPAC name is 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine.

What is Cinnarizine used for?

Cinnarizine is supplied as a characterised reference material related to Cinnarizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cinnarizine can I order?

We supply Cinnarizine in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cinnarizine?

Yes. Every lot of Cinnarizine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cinnarizine be shipped internationally?

Yes. Cinnarizine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.