Thiamine EP Impurity E

Name: Thiamine EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-028327

About Thiamine EP Impurity E

Vaqora Chemicals supplies Thiamine EP Impurity E, a pharmacopeial impurity of Thiamine registered under CAS number 299-35-4. Formula C12H16N4OS2, molecular weight 296.4 g/mol. Its systematic (IUPAC) name is 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione. Common synonyms include Thiamine Hydrochloride - Impurity E and Thiothiamine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Thiamine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Thiamine EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Thiamine

View every impurity, metabolite and intermediate we list for Thiamine.

Thiamine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Thiamine EP Impurity E
Catalogue No.	VQ-028327
CAS Number	299-35-4
IUPAC name	3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione
Molecular formula	C₁₂H₁₆N₄OS₂
Molecular weight	296.4 g/mol
Exact mass	296.0766
Grade	Reference Standard
HSN code	38229090
InChIKey	SQOCQQPFEFRKBV-UHFFFAOYSA-N
SMILES	CC1=C(SC(=S)N1CC2=CN=C(N=C2N)C)CCO
PubChem CID	67530

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	2 / 6
TPSA	133 Å²
Synonyms	Thiamine Hydrochloride - Impurity E, Thiothiamine, Thioxothiamine, Thiothiamin, Thiamin Thiothiazolone, 3-(4-Amino-2-methylpyrimidin-5-ylmethyl)-5-(2-hydroxyethyl)-4-methylthiazole-2(3H)-thione, Thiamine Impurity A, 3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-thiazole-2-thione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements: P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thiamine EP Impurity E?

The CAS Registry Number of Thiamine EP Impurity E is 299-35-4. It is also known as Thiamine Hydrochloride - Impurity E, Thiothiamine, Thioxothiamine.

What is the molecular formula and molecular weight of Thiamine EP Impurity E?

Thiamine EP Impurity E has the molecular formula C12H16N4OS2 and a molecular weight of 296.4 g/mol. Its IUPAC name is 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione.

What is Thiamine EP Impurity E used for?

Thiamine EP Impurity E is supplied as a characterised reference material related to Thiamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thiamine EP Impurity E can I order?

We supply Thiamine EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiamine EP Impurity E?

Yes. Every lot of Thiamine EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiamine EP Impurity E be shipped internationally?

Yes. Thiamine EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.