Tofacitinib Diastereomer

About Tofacitinib Diastereomer

Tofacitinib Diastereomer is an impurity of Tofacitinib carrying the CAS registry number 344418-92-4. The compound has the formula C16H20N6O, corresponding to a molecular weight of 312.37 g/mol. The IUPAC name is 3-[4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile. It is also known as rac-Tofacitinib or racemic-Tasocitinib.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Tofacitinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Tofacitinib Diastereomer in 10 mg and 25 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Tofacitinib Diastereomer
Catalogue No.	VQ-006043
CAS Number	344418-92-4
Other CAS	2664002-63-3
IUPAC name	3-[4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
Molecular formula	C₁₆H₂₀N₆O
Molecular weight	312.37 g/mol
Exact mass	312.1699
Grade	Reference Standard
HSN code	38229090
InChIKey	UJLAWZDWDVHWOW-UHFFFAOYSA-N
SMILES	CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
PubChem CID	9818231

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	1 / 5
TPSA	88.9 Å²
Synonyms	4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile, rac-Tofacitinib, racemic-Tasocitinib, racemic-tofacitinib, Kinome_3438, US10961228, Example Tofacitinib, 1-Piperidinepropanenitrile, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)--oxo-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tofacitinib Diastereomer?

The CAS Registry Number of Tofacitinib Diastereomer is 344418-92-4. It is also known as 4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile, rac-Tofacitinib, racemic-Tasocitinib.

What is the molecular formula and molecular weight of Tofacitinib Diastereomer?

Tofacitinib Diastereomer has the molecular formula C16H20N6O and a molecular weight of 312.37 g/mol. Its IUPAC name is 3-[4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile.

What is Tofacitinib Diastereomer used for?

Tofacitinib Diastereomer is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tofacitinib Diastereomer can I order?

We supply Tofacitinib Diastereomer in Reference Standard grade, in 10 mg, 25 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tofacitinib Diastereomer?

Yes. Every lot of Tofacitinib Diastereomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tofacitinib Diastereomer be shipped internationally?

Yes. We export Tofacitinib Diastereomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.