Cyproheptadine

About Cyproheptadine

Cyproheptadine is a respiratory / antiallergic API (IP/BP/USP grade) carrying the CAS registry number 41354-29-4 with a typical assay of 98.5%. The compound has the formula C42H50Cl2N2O3, corresponding to a molecular weight of 701.8 g/mol. It is also known as Cyproheptadine hydrochloride sesquihydrate or cyproheptadine hydrochloride hydrate.

The product is provided as a solution. Store sealed in a dry, well-ventilated location away from incompatible materials. It carries the GHS signal word “Danger” with 10 hazard statements. Review the Safety Data Sheet before use.

This API belongs to our respiratory and antiallergic APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. It is used across pharmaceutical manufacturing.

Available in 1 kg, 5 kg and 25 kg packs, Cyproheptadine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cyproheptadine
Catalogue No.	VQ-004165
CAS Number	41354-29-4
IUPAC name	bis(1-methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)piperidine);trihydrate;dihydrochloride
Molecular formula	C₄₂H₅₀Cl₂N₂O₃
Molecular weight	701.8 g/mol
Exact mass	700.3198
Grade	IP/BP/USP
Purity / assay	98.5%
HSN code	2933
InChIKey	ZEAUHIZSRUAMQG-UHFFFAOYSA-N
SMILES	CN1CCC(=C2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1.CN1CCC(=C2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1.O.O.O.Cl.Cl
PubChem CID	11954233

Physical properties
Physical form	Solution
Appearance	Appearance: white or almost white powder.(Results:Almost white powder) Solubility: slightly soluble in water, freely,soluble in dilute acetic acid and in methanol,slightly soluble in alcohol.(Results:Complies)
H-bond donors / acceptors	5 / 5
TPSA	9.5 Å²
Synonyms	Cyproheptadine hydrochloride sesquihydrate, cyproheptadine hydrochloride hydrate, 4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride sesquihydrate, 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride sesquihydrate, 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride sesquihydrate, Periactin (TN), Cyproheptadine hydrochloride hydrate(2:2:3), Cyproheptadine hydrochloride (JP18/USP), 4-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine Sesquihydrate, 4-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride hydrate(2:2:3), 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride--water (2/3)

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyproheptadine?

The CAS Registry Number of Cyproheptadine is 41354-29-4. It is also known as Cyproheptadine hydrochloride sesquihydrate, cyproheptadine hydrochloride hydrate, 4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride sesquihydrate.

What is the molecular formula and molecular weight of Cyproheptadine?

Cyproheptadine has the molecular formula C42H50Cl2N2O3 and a molecular weight of 701.8 g/mol.

Which grade and pack sizes of Cyproheptadine can I order?

We supply Cyproheptadine in IP/BP/USP (98.5%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyproheptadine?

Yes. Every lot of Cyproheptadine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyproheptadine be shipped internationally?

Yes. Cyproheptadine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.