Cladribine EP Impurity A

Name: Cladribine EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-022209

About Cladribine EP Impurity A

Cladribine EP Impurity A (CAS 4546-70-7) is a pharmacopeial impurity of Cladribine offered by Vaqora Chemicals. With the molecular formula C10H14N6O3, it has a molar mass of 266.26 g/mol. Its systematic (IUPAC) name is (2R,3S,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol. It is also known as Cladribine - Impurity A or 2-Amino-2'-deoxyadenosine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Cladribine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cladribine

View every impurity, metabolite and intermediate we list for Cladribine.

Cladribine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cladribine EP Impurity A
Catalogue No.	VQ-022209
CAS Number	4546-70-7
IUPAC name	(2R,3S,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Molecular formula	C₁₀H₁₄N₆O₃
Molecular weight	266.26 g/mol
Exact mass	266.1127
Grade	Reference Standard
HSN code	38229090
InChIKey	NOLHIMIFXOBLFF-KVQBGUIXSA-N
SMILES	C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)N)N)CO)O
PubChem CID	97188

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	4 / 8
TPSA	145 Å²
Synonyms	Cladribine - Impurity A, 2-Amino-2'-deoxyadenosine, 2,6-Diaminopurine-2'-deoxyriboside, Adenosine, 2-amino-2'-deoxy-, 2,6-Diaminopurinedeoxyriboside, 2,6-diaminopurine deoxyriboside, 9H-Purine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-2,6-diamino-, 2,6-Diaminopurine 2'-deoxyriboside, (2R,3S,5R)-5-(2,6-diamino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol, 2-amino-deoxyadenosine, 2-Amino-2'-deoxy-D-adenosine, (2R,3S,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cladribine EP Impurity A?

The CAS Registry Number of Cladribine EP Impurity A is 4546-70-7. It is also known as Cladribine - Impurity A, 2-Amino-2'-deoxyadenosine, 2,6-Diaminopurine-2'-deoxyriboside.

What is the molecular formula and molecular weight of Cladribine EP Impurity A?

Cladribine EP Impurity A has the molecular formula C10H14N6O3 and a molecular weight of 266.26 g/mol. Its IUPAC name is (2R,3S,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol.

What is Cladribine EP Impurity A used for?

Cladribine EP Impurity A is supplied as a characterised reference material related to Cladribine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cladribine EP Impurity A can I order?

We supply Cladribine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cladribine EP Impurity A?

Yes. Every lot of Cladribine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cladribine EP Impurity A be shipped internationally?

Yes. We export Cladribine EP Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.