Yohimbine EP Impurity C

About Yohimbine EP Impurity C

Yohimbine EP Impurity C is a pharmacopeial impurity of Yohimbine carrying the CAS registry number 483-10-3. Its molecular formula is C21H26N2O3 and its molecular weight is 354.4 g/mol. Its systematic (IUPAC) name is methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate. Alternative names: Yohimbine Hydrochloride - Impurity C and corynanthine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Yohimbine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Yohimbine

View every impurity, metabolite and intermediate we list for Yohimbine.

Yohimbine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Yohimbine EP Impurity C
Catalogue No.	VQ-024045
CAS Number	483-10-3
IUPAC name	methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Molecular formula	C₂₁H₂₆N₂O₃
Molecular weight	354.4 g/mol
Exact mass	354.1943
Grade	Reference Standard
HSN code	38229090
InChIKey	BLGXFZZNTVWLAY-DKJBZYCGSA-N
SMILES	COC(=O)[C@@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O
PubChem CID	92766

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 4
TPSA	65.6 Å²
Synonyms	Yohimbine Hydrochloride - Impurity C, corynanthine, Rauhimbin, Corynanthin, Methyl (16beta,17alpha)-17-hydroxyyohimban-16-carboxylate, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16beta,17alpha)-, Yohimban-16beta-carboxylic acid, 17alpha-hydroxy-, methyl ester, Methyl 17alpha-hydroxyyohimban-16beta-carboxylate, Yohimban-16.beta.-carboxylic acid, 17.alpha.-hydroxy-, methyl ester, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16.beta.,17.alpha.)-

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Yohimbine EP Impurity C?

The CAS Registry Number of Yohimbine EP Impurity C is 483-10-3. It is also known as Yohimbine Hydrochloride - Impurity C, corynanthine, Rauhimbin.

What is the molecular formula and molecular weight of Yohimbine EP Impurity C?

Yohimbine EP Impurity C has the molecular formula C21H26N2O3 and a molecular weight of 354.4 g/mol. Its IUPAC name is methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate.

What is Yohimbine EP Impurity C used for?

Yohimbine EP Impurity C is supplied as a characterised reference material related to Yohimbine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Yohimbine EP Impurity C can I order?

We supply Yohimbine EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Yohimbine EP Impurity C?

Yes. Every lot of Yohimbine EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Yohimbine EP Impurity C be shipped internationally?

Yes. Yohimbine EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.