Thyropropic acid

Name: Thyropropic acid
Brand: Vaqora Chemicals
SKU: VQ-013824

About Thyropropic acid

Thyropropic acid (CAS 51-26-3) is a process intermediate or related compound of Levothyroxine offered by Vaqora Chemicals. With the molecular formula C15H11I3O4, it has a molar mass of 635.96 g/mol. The IUPAC name is 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid. It is also known as 3,3',5-Triiodo Thyropropionic Acid or Atralose.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Levothyroxine, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	Thyropropic acid
Catalogue No.	VQ-013824
CAS Number	51-26-3
IUPAC name	3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
Molecular formula	C₁₅H₁₁I₃O₄
Molecular weight	635.96 g/mol
Exact mass	635.7792
Grade	Reference Standard
InChIKey	VRORTNGXAKZJML-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CCC(=O)O)I)I)O
PubChem CID	5804

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²
Synonyms	3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid, 3,3',5-Triiodo Thyropropionic Acid, 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodo-benzenepropanoic Acid, 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodo-hydrocinnamic Acid, Atralose, Birodan, 3,3',5-Triiodothyropropionic acid, 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodobenzenepropanoic acid, Acido tiropropico, Triopron, Triprop, Acide thyropropique

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thyropropic acid?

The CAS Registry Number of Thyropropic acid is 51-26-3. It is also known as 3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid, 3,3',5-Triiodo Thyropropionic Acid, 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodo-benzenepropanoic Acid.

What is the molecular formula and molecular weight of Thyropropic acid?

Thyropropic acid has the molecular formula C15H11I3O4 and a molecular weight of 635.96 g/mol. Its IUPAC name is 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid.

What is Thyropropic acid used for?

Thyropropic acid is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thyropropic acid can I order?

We supply Thyropropic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thyropropic acid?

Yes. Every lot of Thyropropic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thyropropic acid be shipped internationally?

Yes. We export Thyropropic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.