2 Chloro 1 3 4 difluorophenyl ethan 1 one

Name: 2 Chloro 1 3 4 difluorophenyl ethan 1 one
Brand: Vaqora Chemicals
SKU: VQ-042523

About 2 Chloro 1 3 4 difluorophenyl ethan 1 one

2 Chloro 1 3 4 difluorophenyl ethan 1 one (CAS 51336-95-9) is an impurity of Ticagrelor offered by Vaqora Chemicals. The compound has the formula C8H5ClF2O, corresponding to a molecular weight of 190.57 g/mol. The IUPAC name is 2-chloro-1-(3,4-difluorophenyl)ethanone. Alternative names: 2-Chloro-1-(3,4-difluoro-phenyl)-ethanone and 2-Chloro-3',4'-difluoroacetophenone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ticagrelor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2 Chloro 1 3 4 difluorophenyl ethan 1 one is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	2 Chloro 1 3 4 difluorophenyl ethan 1 one
Catalogue No.	VQ-042523
CAS Number	51336-95-9
IUPAC name	2-chloro-1-(3,4-difluorophenyl)ethanone
Molecular formula	C₈H₅ClF₂O
Molecular weight	190.57 g/mol
Exact mass	189.9997
Grade	Reference Standard
HSN code	38229090
InChIKey	VMEDAWUIKFAFJQ-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1C(=O)CCl)F)F
PubChem CID	2392321

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	0 / 3
TPSA	17.1 Å²
Synonyms	2-Chloro-1-(3,4-difluoro-phenyl)-ethanone, 2-Chloro-3',4'-difluoroacetophenone, a-Chloro-3,4-difluoroacetophenone, 1-(3,4-difluorophenyl)-2-chloroethan-1-one, 2-Chloro-1-(3,4-difluoro-phenyl)ethanone, Ethanone, 2-chloro-1-(3,4-difluorophenyl)-, 2-chloro-1-(3,4-difluorophenyl) ethanone, 2-Chloro-3 inverted exclamation mark ,4 inverted exclamation mark -difluoroacetophenone

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H290May be corrosive to metals
H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements: P233, P234, P260, P261, P264, P264 + P265, P270, P271, P272, P280, P284, P301 + P316, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P319, P321, P330

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2 Chloro 1 3 4 difluorophenyl ethan 1 one?

The CAS Registry Number of 2 Chloro 1 3 4 difluorophenyl ethan 1 one is 51336-95-9. It is also known as 2-Chloro-1-(3,4-difluoro-phenyl)-ethanone, 2-Chloro-3',4'-difluoroacetophenone, a-Chloro-3,4-difluoroacetophenone.

What is the molecular formula and molecular weight of 2 Chloro 1 3 4 difluorophenyl ethan 1 one?

2 Chloro 1 3 4 difluorophenyl ethan 1 one has the molecular formula C8H5ClF2O and a molecular weight of 190.57 g/mol. Its IUPAC name is 2-chloro-1-(3,4-difluorophenyl)ethanone.

What is 2 Chloro 1 3 4 difluorophenyl ethan 1 one used for?

2 Chloro 1 3 4 difluorophenyl ethan 1 one is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2 Chloro 1 3 4 difluorophenyl ethan 1 one can I order?

We supply 2 Chloro 1 3 4 difluorophenyl ethan 1 one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2 Chloro 1 3 4 difluorophenyl ethan 1 one?

Yes. Every lot of 2 Chloro 1 3 4 difluorophenyl ethan 1 one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2 Chloro 1 3 4 difluorophenyl ethan 1 one be shipped internationally?

Yes. 2 Chloro 1 3 4 difluorophenyl ethan 1 one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.