4,7-Dimethoxy-1-indanone

Name: 4,7-Dimethoxy-1-indanone
Brand: Vaqora Chemicals
SKU: VQ-048076

About 4,7-Dimethoxy-1-indanone

4,7-Dimethoxy-1-indanone (CAS 52428-09-8) is a process intermediate or related compound of Donepezil offered by Vaqora Chemicals. Its molecular formula is C11H12O3 and its molecular weight is 192.21 g/mol. Systematically, it is named 4,7-dimethoxy-2,3-dihydroinden-1-one. Alternative names: 4,7-Dimethoxyindan-1-one and 1H-Inden-1-one, 2,3-dihydro-4,7-dimethoxy-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Donepezil, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Specifications & identifiers

Chemical identifiers
Product name	4,7-Dimethoxy-1-indanone
Catalogue No.	VQ-048076
CAS Number	52428-09-8
IUPAC name	4,7-dimethoxy-2,3-dihydroinden-1-one
Molecular formula	C₁₁H₁₂O₃
Molecular weight	192.21 g/mol
Exact mass	192.0786
InChIKey	MSGQVFMAKBIPNF-UHFFFAOYSA-N
SMILES	COC1=C2CCC(=O)C2=C(C=C1)OC
PubChem CID	606012

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 3
TPSA	35.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,7-Dimethoxy-1-indanone?

The CAS Registry Number of 4,7-Dimethoxy-1-indanone is 52428-09-8. It is also known as 4,7-Dimethoxyindan-1-one, 1H-Inden-1-one, 2,3-dihydro-4,7-dimethoxy-, 4,7-dimethoxy-2,3-dihydro-inden-1-one.

What is the molecular formula and molecular weight of 4,7-Dimethoxy-1-indanone?

4,7-Dimethoxy-1-indanone has the molecular formula C11H12O3 and a molecular weight of 192.21 g/mol. Its IUPAC name is 4,7-dimethoxy-2,3-dihydroinden-1-one.

What is 4,7-Dimethoxy-1-indanone used for?

4,7-Dimethoxy-1-indanone is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,7-Dimethoxy-1-indanone can I order?

We supply 4,7-Dimethoxy-1-indanone, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,7-Dimethoxy-1-indanone?

Yes. Every lot of 4,7-Dimethoxy-1-indanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,7-Dimethoxy-1-indanone be shipped internationally?

Yes. 4,7-Dimethoxy-1-indanone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.