Methotrexate Impurity 26

About Methotrexate Impurity 26

Methotrexate Impurity 26 is an impurity of Methotrexate carrying the CAS registry number 54643-27-5. The compound has the formula C7H8N6O2, corresponding to a molecular weight of 208.18 g/mol. Systematically, it is named 2,4-diamino-6-(hydroxymethyl)-8H-pteridin-7-one. Common synonyms include 2,4-Dhmhp and Methotrexate impurity N4.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Methotrexate impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methotrexate Impurity 26 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	Methotrexate Impurity 26
Catalogue No.	VQ-049078
CAS Number	54643-27-5
IUPAC name	2,4-diamino-6-(hydroxymethyl)-8H-pteridin-7-one
Molecular formula	C₇H₈N₆O₂
Molecular weight	208.18 g/mol
Exact mass	208.0709
Grade	Reference Standard
HSN code	38229090
InChIKey	XYKWYYXXTNGSRG-UHFFFAOYSA-N
SMILES	C(C1=NC2=C(N=C(N=C2NC1=O)N)N)O
PubChem CID	5486846

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.5
H-bond donors / acceptors	4 / 7
TPSA	140 Å²
Synonyms	2,4-Dhmhp, 2,4-Diamino-6-hydroxymethyl-7-hydroxypteridine, 2,4-diamino-6-(hydroxymethyl)pteridin-7(8H)-one, Methotrexate impurity N4, 7(8H)-Pteridinone, 2,4-diamino-6-(hydroxymethyl)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methotrexate Impurity 26?

The CAS Registry Number of Methotrexate Impurity 26 is 54643-27-5. It is also known as 2,4-Dhmhp, 2,4-Diamino-6-hydroxymethyl-7-hydroxypteridine, 2,4-diamino-6-(hydroxymethyl)pteridin-7(8H)-one.

What is the molecular formula and molecular weight of Methotrexate Impurity 26?

Methotrexate Impurity 26 has the molecular formula C7H8N6O2 and a molecular weight of 208.18 g/mol. Its IUPAC name is 2,4-diamino-6-(hydroxymethyl)-8H-pteridin-7-one.

What is Methotrexate Impurity 26 used for?

Methotrexate Impurity 26 is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methotrexate Impurity 26 can I order?

We supply Methotrexate Impurity 26 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methotrexate Impurity 26?

Yes. Every lot of Methotrexate Impurity 26 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methotrexate Impurity 26 be shipped internationally?

Yes. We export Methotrexate Impurity 26 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.