Domperidone

Name: Domperidone
Brand: Vaqora Chemicals
SKU: VQ-004187

About Domperidone

Vaqora Chemicals supplies Domperidone in IP/BP/USP grade, a gastrointestinal API registered under CAS number 57808-66-9. Formula C22H24ClN5O2, molecular weight 425.9 g/mol. Systematically, it is named 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one. It is also known as Motilium or Apo Domperidone.

It is supplied as a white or almost white powder. Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our gastrointestinal APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. It is used across pharmaceutical manufacturing.

We offer Domperidone in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Domperidone

View every impurity, metabolite and intermediate we list for Domperidone.

Domperidone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Domperidone
Catalogue No.	VQ-004187
CAS Number	57808-66-9
IUPAC name	6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Molecular formula	C₂₂H₂₄ClN₅O₂
Molecular weight	425.9 g/mol
Exact mass	425.1619
Grade	IP/BP/USP
HSN code	2933
InChIKey	FGXWKSZFVQUSTL-UHFFFAOYSA-N
SMILES	C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O
PubChem CID	3151

Physical properties
Physical form	Powder
Appearance	White or almost white powder
LogP (XLogP3)	3.9
H-bond donors / acceptors	2 / 3
TPSA	67.9 Å²
Synonyms	Motilium, 5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone, 5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone, Apo Domperidone, Motilium 10, Evoxin, Domilium, Equidone, Vivadone, Nu Domperidone, Equidone Gel, Novo Domperidone

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Domperidone?

The CAS Registry Number of Domperidone is 57808-66-9. It is also known as Motilium, 5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone, 5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone.

What is the molecular formula and molecular weight of Domperidone?

Domperidone has the molecular formula C22H24ClN5O2 and a molecular weight of 425.9 g/mol. Its IUPAC name is 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one.

What is Domperidone used for?

Domperidone is supplied as a characterised reference material related to Domperidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Domperidone can I order?

We supply Domperidone in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Domperidone?

Yes. Every lot of Domperidone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Domperidone be shipped internationally?

Yes. Domperidone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.