Promethazine Hydrochloride

Name: Promethazine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-041702

About Promethazine Hydrochloride

Promethazine Hydrochloride (CAS 58-33-3) is a high-purity reference standard of Promethazine offered by Vaqora Chemicals. With the molecular formula C17H21ClN2S, it has a molar mass of 320.9 g/mol. It is also known as Promethazine Hcl or Diprasine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Promethazine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Promethazine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Promethazine

View every impurity, metabolite and intermediate we list for Promethazine.

Promethazine impurities

Specifications & identifiers

Chemical identifiers
Product name	Promethazine Hydrochloride
Catalogue No.	VQ-041702
CAS Number	58-33-3
IUPAC name	N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride
Molecular formula	C₁₇H₂₁ClN₂S
Molecular weight	320.9 g/mol
Exact mass	320.1114
Grade	Reference Standard
HSN code	38229090
InChIKey	XXPDBLUZJRXNNZ-UHFFFAOYSA-N
SMILES	CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl
PubChem CID	6014

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 3
TPSA	31.8 Å²
Synonyms	Promethazine Hcl, Diprasine, Fellozine, Prometh Fortis, Prometh Plain, Mymethazine Fortis, Anergan 25, Kinetosin, Promantine, Primine, Promethazine chloride, Zipan-25

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Promethazine Hydrochloride?

The CAS Registry Number of Promethazine Hydrochloride is 58-33-3. It is also known as Promethazine Hcl, Diprasine, Fellozine.

What is the molecular formula and molecular weight of Promethazine Hydrochloride?

Promethazine Hydrochloride has the molecular formula C17H21ClN2S and a molecular weight of 320.9 g/mol.

What is Promethazine Hydrochloride used for?

Promethazine Hydrochloride is supplied as a characterised reference material related to Promethazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Promethazine Hydrochloride can I order?

We supply Promethazine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Promethazine Hydrochloride?

Yes. Every lot of Promethazine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Promethazine Hydrochloride be shipped internationally?

Yes. Promethazine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.