Thiocolchicoside

Name: Thiocolchicoside
Brand: Vaqora Chemicals
SKU: VQ-004017

About Thiocolchicoside

Listed under CAS 602-41-5, Thiocolchicoside is an analgesic / anti-inflammatory API available from Vaqora Chemicals in IP/BP/USP grade. Formula C27H33NO10S, molecular weight 563.6 g/mol. Common synonyms include Coltramyl and Musco-ril.

The product is provided as a powder. Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our analgesic and anti-inflammatory APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Typical end-use sectors are pharmaceutical manufacturing.

Standard pack sizes are 1 kg, 5 kg and 25 kg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Thiocolchicoside
Catalogue No.	VQ-004017
CAS Number	602-41-5
IUPAC name	N-[(7S)-1,2-dimethoxy-10-methylsulfanyl-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Molecular formula	C₂₇H₃₃NO₁₀S
Molecular weight	563.6 g/mol
Exact mass	563.1825
Grade	IP/BP/USP
HSN code	2933
InChIKey	LEQAKWQJCITZNK-AXHKHJLKSA-N
SMILES	CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O
PubChem CID	9915886

Physical properties
Physical form	Powder
LogP (XLogP3)	-0.4
H-bond donors / acceptors	5 / 11
TPSA	189 Å²
Synonyms	Coltramyl, Musco-ril, Tiocolchicoside, 2-10-Di(demethoxy)-2-glucosyloxy-10-methylthiocolchicine, 2,14-di-(demethoxy)-2-glucosidoxy-14-methylthiocolchicine, 10-Thiocolchicoside, Thiocolchicoside (INN), Colchicoside, 10-thio-, R. 271, Tiocolchicoside [DCIT], Coltramyl (TN), Thiocolchicoside (Standard)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H335May cause respiratory irritation
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P263, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P318, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thiocolchicoside?

The CAS Registry Number of Thiocolchicoside is 602-41-5. It is also known as Coltramyl, Musco-ril, Tiocolchicoside.

What is the molecular formula and molecular weight of Thiocolchicoside?

Thiocolchicoside has the molecular formula C27H33NO10S and a molecular weight of 563.6 g/mol.

Which grade and pack sizes of Thiocolchicoside can I order?

We supply Thiocolchicoside in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiocolchicoside?

Yes. Every lot of Thiocolchicoside is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiocolchicoside be shipped internationally?

Yes. Thiocolchicoside is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.