Selumetinib Impurity 21

Name: Selumetinib Impurity 21
Brand: Vaqora Chemicals
SKU: VQ-005871

About Selumetinib Impurity 21

Listed under CAS 606144-04-1, Selumetinib Impurity 21 is an impurity of Selumetinib available from Vaqora Chemicals with a typical assay of 97%. Formula C15H10BrClFN3O2, molecular weight 398.61 g/mol. The IUPAC name is 6-(4-bromo-2-chloroanilino)-7-fluoro-3-methylbenzimidazole-5-carboxylic acid. Common synonyms include Selumetinib metabolite M15 and CS-M0259.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Selumetinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Selumetinib Impurity 21 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Selumetinib

View every impurity, metabolite and intermediate we list for Selumetinib.

Selumetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Selumetinib Impurity 21
Catalogue No.	VQ-005871
CAS Number	606144-04-1
IUPAC name	6-(4-bromo-2-chloroanilino)-7-fluoro-3-methylbenzimidazole-5-carboxylic acid
Molecular formula	C₁₅H₁₀BrClFN₃O₂
Molecular weight	398.61 g/mol
Exact mass	396.9629
Grade	Reference Standard
Purity / assay	97%
HSN code	38229090
InChIKey	XAAPQRFIXGDKPZ-UHFFFAOYSA-N
SMILES	CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)O
PubChem CID	16092137

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	2 / 5
TPSA	67.2 Å²
Synonyms	5-[(4-Bromo-2-chlorophenyl)amino]-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylic acid, 6-(4-Bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzo[d]imidazole-5-carboxylic acid, 6-(4-Bromo-2-chlorophenylamino)-7-fluoro-3-methyl-benzimidazole-5-carboxylic acid, 5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid, 5-(4-bromo-2-chlorophenylamino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid, Selumetinib metabolite M15, 1H-Benzimidazole-6-carboxylic acid, 5-((4-bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-, 5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylic acid, 6-(4-Bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzo(d)imidazole-5-carboxylic acid, CS-M0259, 5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylicacid, 5-(4-Bromo-2-chloroanilino)-4-fluoro-1-methyl-1H-1,3-benzimidazole-6-carboxylic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Selumetinib Impurity 21?

The CAS Registry Number of Selumetinib Impurity 21 is 606144-04-1. It is also known as 5-[(4-Bromo-2-chlorophenyl)amino]-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylic acid, 6-(4-Bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzo[d]imidazole-5-carboxylic acid, 6-(4-Bromo-2-chlorophenylamino)-7-fluoro-3-methyl-benzimidazole-5-carboxylic acid.

What is the molecular formula and molecular weight of Selumetinib Impurity 21?

Selumetinib Impurity 21 has the molecular formula C15H10BrClFN3O2 and a molecular weight of 398.61 g/mol. Its IUPAC name is 6-(4-bromo-2-chloroanilino)-7-fluoro-3-methylbenzimidazole-5-carboxylic acid.

What is Selumetinib Impurity 21 used for?

Selumetinib Impurity 21 is supplied as a characterised reference material related to Selumetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Selumetinib Impurity 21 can I order?

We supply Selumetinib Impurity 21 in Reference Standard (97%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Selumetinib Impurity 21?

Yes. Every lot of Selumetinib Impurity 21 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Selumetinib Impurity 21 be shipped internationally?

Yes. We export Selumetinib Impurity 21 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.