Nintedanib

Name: Nintedanib
Brand: Vaqora Chemicals
SKU: VQ-007618

About Nintedanib

Vaqora Chemicals supplies Nintedanib, a high-purity reference standard of Nintedanib registered under CAS number 656247-17-5. Its molecular formula is C31H33N5O4 and its molecular weight is 539.6 g/mol. Common synonyms include BIBF 1120 and Ofev.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Nintedanib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nintedanib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib
Catalogue No.	VQ-007618
CAS Number	656247-17-5
Other CAS	656247-18-6
IUPAC name	methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
Molecular formula	C₃₁H₃₃N₅O₄
Molecular weight	539.6 g/mol
Exact mass	539.2533
Grade	Reference Standard
HSN code	38229090
InChIKey	CPMDPSXJELVGJG-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
PubChem CID	135423438

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 7
TPSA	101 Å²
Synonyms	BIBF 1120, Ofev, Vargatef, BIBF-1120, Nintedanib (BIBF 1120), Ofev (TN), Nintedanib E-isomer, (E)-Nintedanib, Nintedanib (Standard), BIBF1120,Vargatef, Nintedanib (free base), Nintedanib (USAN/INN)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib?

The CAS Registry Number of Nintedanib is 656247-17-5. It is also known as BIBF 1120, Ofev, Vargatef.

What is the molecular formula and molecular weight of Nintedanib?

Nintedanib has the molecular formula C31H33N5O4 and a molecular weight of 539.6 g/mol. Its IUPAC name is methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate.

What is Nintedanib used for?

Nintedanib is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib can I order?

We supply Nintedanib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib?

Yes. Every lot of Nintedanib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib be shipped internationally?

Yes. We export Nintedanib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.