Imidazole-D3

About Imidazole-D3

Imidazole-D3 is a stable isotope labelled analogue related to Histidine carrying the CAS registry number 6745-43-3. Formula C3H4N2, molecular weight 71.1 g/mol. Systematically, it is named 2,4,5-trideuterio-1H-imidazole. Alternative names: imidazole-d and 1H-imidazole-2,4,5-d3.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Histidine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Imidazole-D3 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Histidine

View every impurity, metabolite and intermediate we list for Histidine.

Histidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Imidazole-D3
Catalogue No.	VQ-041197
CAS Number	6745-43-3
IUPAC name	2,4,5-trideuterio-1H-imidazole
Molecular formula	C₃H₄N₂
Molecular weight	71.1 g/mol
Exact mass	71.0563
Grade	Reference Standard
HSN code	38229090
InChIKey	RAXXELZNTBOGNW-CBYSEHNBSA-N
SMILES	[2H]C1=C(N=C(N1)[2H])[2H]
PubChem CID	129731321

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	1 / 1
TPSA	28.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Imidazole-D3?

The CAS Registry Number of Imidazole-D3 is 6745-43-3. It is also known as imidazole-d, 1H-imidazole-2,4,5-d3.

What is the molecular formula and molecular weight of Imidazole-D3?

Imidazole-D3 has the molecular formula C3H4N2 and a molecular weight of 71.1 g/mol. Its IUPAC name is 2,4,5-trideuterio-1H-imidazole.

What is Imidazole-D3 used for?

Imidazole-D3 is supplied as a characterised reference material related to Histidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Imidazole-D3 can I order?

We supply Imidazole-D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Imidazole-D3?

Yes. Every lot of Imidazole-D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Imidazole-D3 be shipped internationally?

Yes. We export Imidazole-D3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.