Levothyroxine Sodium EP Impurity J

Name: Levothyroxine Sodium EP Impurity J
Brand: Vaqora Chemicals
SKU: VQ-045221

About Levothyroxine Sodium EP Impurity J

Listed under CAS 70-40-6, Levothyroxine Sodium EP Impurity J is a pharmacopeial impurity of Levothyroxine available from Vaqora Chemicals. Its molecular formula is C15H13I2NO4 and its molecular weight is 525.08 g/mol. Its systematic (IUPAC) name is 2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid. Common synonyms include rac-Levothyroxine EP Impurity J and 3,3'-Diiodothyronine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Levothyroxine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Levothyroxine Sodium EP Impurity J is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine Sodium EP Impurity J
Catalogue No.	VQ-045221
CAS Number	70-40-6
IUPAC name	2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
Molecular formula	C₁₅H₁₃I₂NO₄
Molecular weight	525.08 g/mol
Exact mass	524.8934
Grade	Reference Standard
HSN code	38229090
InChIKey	CPCJBZABTUOGNM-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1CC(C(=O)O)N)I)OC2=CC(=C(C=C2)O)I
PubChem CID	65559

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	3 / 5
TPSA	92.8 Å²
Synonyms	rac-Levothyroxine EP Impurity J, 3,3'-Diiodothyronine, O-(4-hydroxy-3-iodophenyl)-3-iodotyrosine, 3,3'-T2, Tyrosine, O-(4-hydroxy-3-iodophenyl)-3-iodo-, 2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl)propanoic acid, 3,3'-diiodthyronin, 3,3\'-diiodo-L-thyronine, (2S)-2-amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propanoic acid, US10322118, Entry 4, 2-amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propanoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine Sodium EP Impurity J?

The CAS Registry Number of Levothyroxine Sodium EP Impurity J is 70-40-6. It is also known as rac-Levothyroxine EP Impurity J, 3,3'-Diiodothyronine, O-(4-hydroxy-3-iodophenyl)-3-iodotyrosine.

What is the molecular formula and molecular weight of Levothyroxine Sodium EP Impurity J?

Levothyroxine Sodium EP Impurity J has the molecular formula C15H13I2NO4 and a molecular weight of 525.08 g/mol. Its IUPAC name is 2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid.

What is Levothyroxine Sodium EP Impurity J used for?

Levothyroxine Sodium EP Impurity J is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine Sodium EP Impurity J can I order?

We supply Levothyroxine Sodium EP Impurity J in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine Sodium EP Impurity J?

Yes. Every lot of Levothyroxine Sodium EP Impurity J is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine Sodium EP Impurity J be shipped internationally?

Yes. We export Levothyroxine Sodium EP Impurity J worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.