Cimetidine EP Impurity H

Name: Cimetidine EP Impurity H
Brand: Vaqora Chemicals
SKU: VQ-021154

About Cimetidine EP Impurity H

Vaqora Chemicals supplies Cimetidine EP Impurity H, a pharmacopeial impurity of Cimetidine registered under CAS number 74886-59-2. With the molecular formula C10H18N8S2, it has a molar mass of 314.4 g/mol. Its systematic (IUPAC) name is 1-cyano-3-[2-[2-[(N-cyano-N'-methylcarbamimidoyl)amino]ethyldisulfanyl]ethyl]-2-methylguanidine. Common synonyms include Cimetidine Hydrochloride - Impurity H and Cimet idine impurity H.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Cimetidine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cimetidine EP Impurity H is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cimetidine

View every impurity, metabolite and intermediate we list for Cimetidine.

Cimetidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cimetidine EP Impurity H
Catalogue No.	VQ-021154
CAS Number	74886-59-2
IUPAC name	1-cyano-3-[2-[2-[(N-cyano-N'-methylcarbamimidoyl)amino]ethyldisulfanyl]ethyl]-2-methylguanidine
Molecular formula	C₁₀H₁₈N₈S₂
Molecular weight	314.4 g/mol
Exact mass	314.1096
Grade	Reference Standard
HSN code	38229090
InChIKey	TVTGYLDJRZJUDE-UHFFFAOYSA-N
SMILES	CN=C(NCCSSCCNC(=NC)NC#N)NC#N
PubChem CID	14457221

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	4 / 6
TPSA	171 Å²
Synonyms	Cimetidine Hydrochloride - Impurity H, 1,1'-(Disulphanediyldiethylene)bis(2-cyano-3-methylguanidine), 1,1'-(disulfanediylbis(ethane-2,1-diyl))bis(2'-cyano-3-methylguanidine), Cimet idine impurity H, Cimetidine Impurity 15, N-Cyano-3-(cyanoamino)-N'-methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-imidamide, N,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine, 3,3'-(3,4-Dithiahexane-1,6-diyl)bis[(2-cyano-1-methyl)guanidine], 7,8-Dithia-2,4,11-triazadodec-2-en-12-imidamide, N-cyano-3-(cyanoamino)-N'-methyl-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P264, P270, P271, P284, P301 + P317, P304 + P340, P330, P342 + P316, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cimetidine EP Impurity H?

The CAS Registry Number of Cimetidine EP Impurity H is 74886-59-2. It is also known as Cimetidine Hydrochloride - Impurity H, 1,1'-(Disulphanediyldiethylene)bis(2-cyano-3-methylguanidine), 1,1'-(disulfanediylbis(ethane-2,1-diyl))bis(2'-cyano-3-methylguanidine).

What is the molecular formula and molecular weight of Cimetidine EP Impurity H?

Cimetidine EP Impurity H has the molecular formula C10H18N8S2 and a molecular weight of 314.4 g/mol. Its IUPAC name is 1-cyano-3-[2-[2-[(N-cyano-N'-methylcarbamimidoyl)amino]ethyldisulfanyl]ethyl]-2-methylguanidine.

What is Cimetidine EP Impurity H used for?

Cimetidine EP Impurity H is supplied as a characterised reference material related to Cimetidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cimetidine EP Impurity H can I order?

We supply Cimetidine EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cimetidine EP Impurity H?

Yes. Every lot of Cimetidine EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cimetidine EP Impurity H be shipped internationally?

Yes. Cimetidine EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.