(2R,4S)-Sacubitril

Name: (2R,4S)-Sacubitril
Brand: Vaqora Chemicals
SKU: VQ-012746

About (2R,4S)-Sacubitril

Listed under CAS 761373-05-1, (2R,4S)-Sacubitril is a process intermediate or related compound of Sacubitril available from Vaqora Chemicals. With the molecular formula C24H29NO5, it has a molar mass of 411.5 g/mol. Its systematic (IUPAC) name is 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid. Common synonyms include Sacubitril, (2R,4S)- and 2R,4S-Sacubitril.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Sacubitril, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (2R,4S)-Sacubitril in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,4S)-Sacubitril
Catalogue No.	VQ-012746
CAS Number	761373-05-1
Other CAS	3081732-56-8
IUPAC name	4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid
Molecular formula	C₂₄H₂₉NO₅
Molecular weight	411.5 g/mol
Exact mass	411.2046
Grade	Reference Standard
HSN code	2933
InChIKey	PYNXFZCZUAOOQC-LAUBAEHRSA-N
SMILES	CCOC(=O)[C@@H](C)C[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O
PubChem CID	9978992

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 5
TPSA	92.7 Å²
Synonyms	4-Ethyl (αS,γR)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, (2R,4S)-Sacubitril, Sacubitril, (2R,4S)-, 2R,4S-Sacubitril, (2S,4R)-Sacubitril, ahu377 isomer 2, CS-M3545

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,4S)-Sacubitril?

The CAS Registry Number of (2R,4S)-Sacubitril is 761373-05-1. It is also known as 4-Ethyl (αS,γR)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, (2R,4S)-Sacubitril, Sacubitril, (2R,4S)-.

What is the molecular formula and molecular weight of (2R,4S)-Sacubitril?

(2R,4S)-Sacubitril has the molecular formula C24H29NO5 and a molecular weight of 411.5 g/mol. Its IUPAC name is 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid.

What is (2R,4S)-Sacubitril used for?

(2R,4S)-Sacubitril is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,4S)-Sacubitril can I order?

We supply (2R,4S)-Sacubitril in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,4S)-Sacubitril?

Yes. Every lot of (2R,4S)-Sacubitril is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,4S)-Sacubitril be shipped internationally?

Yes. We export (2R,4S)-Sacubitril worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.