Famotidine

About Famotidine

Famotidine is a gastrointestinal API in IP/BP/USP grade carrying the CAS registry number 76824-35-6 at a purity of 98.5%. Its molecular formula is C8H15N7O2S3 and its molecular weight is 337.5 g/mol. Systematically, it is named 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide. Common synonyms include Gastridin and Pepdine.

It is supplied as a solution. Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our gastrointestinal APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Buyers come mainly from pharmaceutical manufacturing.

We offer Famotidine in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Famotidine

View every impurity, metabolite and intermediate we list for Famotidine.

Famotidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Famotidine
Catalogue No.	VQ-004190
CAS Number	76824-35-6
IUPAC name	3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide
Molecular formula	C₈H₁₅N₇O₂S₃
Molecular weight	337.5 g/mol
Exact mass	337.0449
Grade	IP/BP/USP
Purity / assay	98.5%
HSN code	2933
InChIKey	XUFQPHANEAPEMJ-UHFFFAOYSA-N
SMILES	C1=C(N=C(S1)N=C(N)N)CSCC/C(=N/S(=O)(=O)N)/N
PubChem CID	5702160

Physical properties
Physical form	Solution
Appearance	A white or yellowish white crystalline,powder or crystals, very soluble in water,very slightly soluble in ethanol, slightly soluble in glacial acetic acid.(Results:Conform)
LogP (XLogP3)	-0.6
H-bond donors / acceptors	4 / 8
TPSA	238 Å²
Synonyms	Gastridin, Pepdine, Pepcidine, Famoxal, Pepcid AC, MK-208, Pepcid RPD, MK 208, Major heartburn relief, 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide, (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide, N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Famotidine?

The CAS Registry Number of Famotidine is 76824-35-6. It is also known as Gastridin, Pepdine, Pepcidine.

What is the molecular formula and molecular weight of Famotidine?

Famotidine has the molecular formula C8H15N7O2S3 and a molecular weight of 337.5 g/mol. Its IUPAC name is 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide.

What is Famotidine used for?

Famotidine is supplied as a characterised reference material related to Famotidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Famotidine can I order?

We supply Famotidine in IP/BP/USP (98.5%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Famotidine?

Yes. Every lot of Famotidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Famotidine be shipped internationally?

Yes. Famotidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.