Fluticasone USP Related Compound C

About Fluticasone USP Related Compound C

Fluticasone USP Related Compound C is a pharmacopeial impurity of Fluticasone carrying the CAS registry number 80474-24-4. With the molecular formula C24H29F3O5S, it has a molar mass of 486.5 g/mol. Common synonyms include Fluticasone Acetate and Fluticasone Propionate EP Impurity C.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Fluticasone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Fluticasone USP Related Compound C in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Fluticasone

View every impurity, metabolite and intermediate we list for Fluticasone.

Fluticasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Fluticasone USP Related Compound C
Catalogue No.	VQ-006402
CAS Number	80474-24-4
IUPAC name	[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate
Molecular formula	C₂₄H₂₉F₃O₅S
Molecular weight	486.5 g/mol
Exact mass	486.1688
Grade	Reference Standard
HSN code	38229090
InChIKey	ODNKIHMUIGPTII-OSNGSNEUSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)SCF)OC(=O)C)C)O)F)C)F
PubChem CID	10005640

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 9
TPSA	106 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fluticasone USP Related Compound C?

The CAS Registry Number of Fluticasone USP Related Compound C is 80474-24-4. It is also known as Fluticasone Acetate, Fluticasone Propionate EP Impurity C, Fluticasone Furoate EP Impurity B.

What is the molecular formula and molecular weight of Fluticasone USP Related Compound C?

Fluticasone USP Related Compound C has the molecular formula C24H29F3O5S and a molecular weight of 486.5 g/mol.

What is Fluticasone USP Related Compound C used for?

Fluticasone USP Related Compound C is supplied as a characterised reference material related to Fluticasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fluticasone USP Related Compound C can I order?

We supply Fluticasone USP Related Compound C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fluticasone USP Related Compound C?

Yes. Every lot of Fluticasone USP Related Compound C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fluticasone USP Related Compound C be shipped internationally?

Yes. Fluticasone USP Related Compound C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.