Fluticasone Propionate

Name: Fluticasone Propionate
Brand: Vaqora Chemicals
SKU: VQ-004172

About Fluticasone Propionate

Fluticasone Propionate (CAS 80474-14-2) is a respiratory / antiallergic API offered by Vaqora Chemicals (IP/BP/USP grade). Formula C25H31F3O5S, molecular weight 500.6 g/mol. Common synonyms include Cutivate and Flixotide.

It is supplied as a white powder. Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Danger” with 8 hazard statements. Review the Safety Data Sheet before use.

This API belongs to our respiratory and antiallergic APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Our customers for this product work in pharmaceutical manufacturing.

Standard pack sizes are 1 kg, 5 kg and 25 kg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Fluticasone

View every impurity, metabolite and intermediate we list for Fluticasone.

Fluticasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Fluticasone Propionate
Catalogue No.	VQ-004172
CAS Number	80474-14-2
IUPAC name	[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Molecular formula	C₂₅H₃₁F₃O₅S
Molecular weight	500.6 g/mol
Exact mass	500.1844
Grade	IP/BP/USP
InChIKey	WMWTYOKRWGGJOA-CENSZEJFSA-N
SMILES	CCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCF
PubChem CID	444036

Physical properties
Physical form	Powder
Appearance	White powder
LogP (XLogP3)	4
H-bond donors / acceptors	1 / 9
TPSA	106 Å²
Synonyms	Cutivate, Flixotide, Flovent HFA, Flovent Diskus, Flovent Diskus 50, Flovent Diskus 100, Flovent Diskus 250, ArmonAir RespiClick, Fluticasone-17-propionate, Flonase Allergy Relief, childrens nasal, Aerivio Spiromax

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301 + P317, P302 + P352, P304 + P340, P318, P319, P321, P330, P333 + P317, P342 + P316, P362 + P364, P391, P403, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fluticasone Propionate?

The CAS Registry Number of Fluticasone Propionate is 80474-14-2. It is also known as Cutivate, Flixotide, Flovent HFA.

What is the molecular formula and molecular weight of Fluticasone Propionate?

Fluticasone Propionate has the molecular formula C25H31F3O5S and a molecular weight of 500.6 g/mol.

What is Fluticasone Propionate used for?

Fluticasone Propionate is supplied as a characterised reference material related to Fluticasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fluticasone Propionate can I order?

We supply Fluticasone Propionate in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fluticasone Propionate?

Yes. Every lot of Fluticasone Propionate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fluticasone Propionate be shipped internationally?

Yes. Fluticasone Propionate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.