1-Hydroxymidazolam β-D-glucuronide

Name: 1-Hydroxymidazolam β-D-glucuronide
Brand: Vaqora Chemicals
SKU: VQ-044841

About 1-Hydroxymidazolam β-D-glucuronide

Listed under CAS 81256-81-7, 1-Hydroxymidazolam β-D-glucuronide is a metabolite or degradation product of Midazolam available from Vaqora Chemicals. The compound has the formula C24H21ClFN3O7, corresponding to a molecular weight of 517.9 g/mol. Common synonyms include Mdz-glucuronide and 1-Hydroxymethylmidazolam glucuronide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Midazolam, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-Hydroxymidazolam β-D-glucuronide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Midazolam

View every impurity, metabolite and intermediate we list for Midazolam.

Midazolam impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Hydroxymidazolam β-D-glucuronide
Catalogue No.	VQ-044841
CAS Number	81256-81-7
IUPAC name	(2S,3S,4S,5R,6R)-6-[[8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Molecular formula	C₂₄H₂₁ClFN₃O₇
Molecular weight	517.9 g/mol
Exact mass	517.1052
Grade	Reference Standard
HSN code	38229090
InChIKey	ICIUMXQTLQXWGL-QMDPOKHVSA-N
SMILES	C1C2=CN=C(N2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4F)CO[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)C(=O)O)O)O)O
PubChem CID	133640

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	4 / 10
TPSA	147 Å²
Synonyms	Mdz-glucuronide, 1-Hydroxymethylmidazolam glucuronide, 1'-Hydroxy Midazolam-beta-D-glucuronide, 1'-Hydroxy Midazolam-b-D-glucuronide, 1'-Hydroxymidazolam, A-D-Glucuronide, 1'-hydroxymidazolam beta-D-glucuronide, 1'-Hydroxy Midazolam-, A-D-glucuronide, 1'-OH MDZ glucuronide, 1-hydroxymidazolam glucuronide, 1'-hydroxymidazolam-glucuronide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Hydroxymidazolam β-D-glucuronide?

The CAS Registry Number of 1-Hydroxymidazolam β-D-glucuronide is 81256-81-7. It is also known as Mdz-glucuronide, 1-Hydroxymethylmidazolam glucuronide, 1'-Hydroxy Midazolam-beta-D-glucuronide.

What is the molecular formula and molecular weight of 1-Hydroxymidazolam β-D-glucuronide?

1-Hydroxymidazolam β-D-glucuronide has the molecular formula C24H21ClFN3O7 and a molecular weight of 517.9 g/mol. Its IUPAC name is (2S,3S,4S,5R,6R)-6-[[8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.

What is 1-Hydroxymidazolam β-D-glucuronide used for?

1-Hydroxymidazolam β-D-glucuronide is supplied as a characterised reference material related to Midazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Hydroxymidazolam β-D-glucuronide can I order?

We supply 1-Hydroxymidazolam β-D-glucuronide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Hydroxymidazolam β-D-glucuronide?

Yes. Every lot of 1-Hydroxymidazolam β-D-glucuronide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Hydroxymidazolam β-D-glucuronide be shipped internationally?

Yes. We export 1-Hydroxymidazolam β-D-glucuronide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.