Sitagliptin Hydrochloride Hydrate

About Sitagliptin Hydrochloride Hydrate

Sitagliptin Hydrochloride Hydrate is a high-purity reference standard of Sitagliptin carrying the CAS registry number 862156-92-1. Formula C16H18ClF6N5O2, molecular weight 461.79 g/mol. It is also known as Sitagliptin Monohydrochloride Monohydrate or Sitagliptin hydrochloride monohydrate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Sitagliptin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin Hydrochloride Hydrate
Catalogue No.	VQ-007758
CAS Number	862156-92-1
Other CAS	486460-32-6, 486459-71-6, 654671-78-0
IUPAC name	(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrate;hydrochloride
Molecular formula	C₁₆H₁₈ClF₆N₅O₂
Molecular weight	461.79 g/mol
Exact mass	461.1053
Grade	Reference Standard
HSN code	38229090
InChIKey	YPULIQLVSSZRST-KLQYNRQASA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.O.Cl
PubChem CID	91827430

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 11
TPSA	78 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin Hydrochloride Hydrate?

The CAS Registry Number of Sitagliptin Hydrochloride Hydrate is 862156-92-1. It is also known as Sitagliptin Monohydrochloride Monohydrate, Sitagliptin hydrochloride monohydrate, Brynovin (TN).

What is the molecular formula and molecular weight of Sitagliptin Hydrochloride Hydrate?

Sitagliptin Hydrochloride Hydrate has the molecular formula C16H18ClF6N5O2 and a molecular weight of 461.79 g/mol.

What is Sitagliptin Hydrochloride Hydrate used for?

Sitagliptin Hydrochloride Hydrate is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin Hydrochloride Hydrate can I order?

We supply Sitagliptin Hydrochloride Hydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin Hydrochloride Hydrate?

Yes. Every lot of Sitagliptin Hydrochloride Hydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin Hydrochloride Hydrate be shipped internationally?

Yes. Sitagliptin Hydrochloride Hydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.