Crizotinib Amine Impurity

Name: Crizotinib Amine Impurity
Brand: Vaqora Chemicals
SKU: VQ-025092

About Crizotinib Amine Impurity

Vaqora Chemicals supplies Crizotinib Amine Impurity, an impurity of Crizotinib registered under CAS number 877397-71-2. Its molecular formula is C13H11Cl2FN2O and its molecular weight is 301.14 g/mol. Systematically, it is named 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine. It is also known as Carbofuran Impurity 3 or CS-M0265.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Crizotinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Crizotinib Amine Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Crizotinib

View every impurity, metabolite and intermediate we list for Crizotinib.

Crizotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Crizotinib Amine Impurity
Catalogue No.	VQ-025092
CAS Number	877397-71-2
IUPAC name	3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine
Molecular formula	C₁₃H₁₁Cl₂FN₂O
Molecular weight	301.14 g/mol
Exact mass	300.0232
Grade	Reference Standard
HSN code	38229090
InChIKey	IEKMAKBQCRKWLS-SSDOTTSWSA-N
SMILES	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC=C2)N
PubChem CID	49765905

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	1 / 4
TPSA	48.1 Å²
Synonyms	(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine, 3-[[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-2-amine, 2-Pyridinamine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-, Carbofuran Impurity 3, CS-M0265, (1R)-1-(2.6-dichloro-3-fluorophenyl)ethoxylpyridin-2-amine, (R)-3-(1-(26-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine, (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethyoxyl)-2-aminopyridine, 3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine, (R)-, 3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine, 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl) ethoxy]pyridin-2-amine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Crizotinib Amine Impurity?

The CAS Registry Number of Crizotinib Amine Impurity is 877397-71-2. It is also known as (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine, 3-[[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-2-amine, 2-Pyridinamine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-.

What is the molecular formula and molecular weight of Crizotinib Amine Impurity?

Crizotinib Amine Impurity has the molecular formula C13H11Cl2FN2O and a molecular weight of 301.14 g/mol. Its IUPAC name is 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine.

What is Crizotinib Amine Impurity used for?

Crizotinib Amine Impurity is supplied as a characterised reference material related to Crizotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Crizotinib Amine Impurity can I order?

We supply Crizotinib Amine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Crizotinib Amine Impurity?

Yes. Every lot of Crizotinib Amine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Crizotinib Amine Impurity be shipped internationally?

Yes. We export Crizotinib Amine Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.