Glimepiride

About Glimepiride

Glimepiride is a metabolic / hormonal API in IP/BP/USP grade carrying the CAS registry number 93479-97-1. The compound has the formula C24H34N4O5S, corresponding to a molecular weight of 490.6 g/mol. Its systematic (IUPAC) name is 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide. Alternative names: Amaryl and cis-Glimepiride.

It is supplied as a powder. Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This API belongs to our antidiabetic, hormone and metabolic APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Our customers for this product work in pharmaceutical manufacturing.

Available in 1 kg, 5 kg and 25 kg packs, Glimepiride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Glimepiride

View every impurity, metabolite and intermediate we list for Glimepiride.

Glimepiride impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Glimepiride
Catalogue No.	VQ-004132
CAS Number	93479-97-1
IUPAC name	4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide
Molecular formula	C₂₄H₃₄N₄O₅S
Molecular weight	490.6 g/mol
Exact mass	490.225
Grade	IP/BP/USP
HSN code	2933
InChIKey	WIGIZIANZCJQQY-UHFFFAOYSA-N
SMILES	CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C
PubChem CID	3476

Physical properties
Physical form	Powder
LogP (XLogP3)	3.9
H-bond donors / acceptors	3 / 5
TPSA	133 Å²
Synonyms	Amaryl, cis-Glimepiride, Endial, Hoe-490, Glimepride, HOE 490, Glimepiride, cis-, SL-NH2 Trifluoroacetic Acid Salt (1:2), Ristomycin Monosulfate (90%), Ristocetin Sulfate, Ristomycin Sulfate, Amaryl (TN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Glimepiride?

The CAS Registry Number of Glimepiride is 93479-97-1. It is also known as Amaryl, cis-Glimepiride, Endial.

What is the molecular formula and molecular weight of Glimepiride?

Glimepiride has the molecular formula C24H34N4O5S and a molecular weight of 490.6 g/mol. Its IUPAC name is 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide.

What is Glimepiride used for?

Glimepiride is supplied as a characterised reference material related to Glimepiride. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Glimepiride can I order?

We supply Glimepiride in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Glimepiride?

Yes. Every lot of Glimepiride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Glimepiride be shipped internationally?

Yes. Glimepiride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.