Disulfiram

About Disulfiram

Disulfiram is an active pharmaceutical ingredient in IP/BP/USP grade carrying the CAS registry number 97-77-8. Formula C10H20N2S4, molecular weight 296.5 g/mol. Systematically, it is named diethylcarbamothioylsulfanyl N,N-diethylcarbamodithioate. Common synonyms include Tetraethylthiuram disulfide and Bis(diethylthiocarbamoyl) disulfide.

The product is provided as a powder. Store sealed in a dry, well-ventilated location away from incompatible materials. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As an active pharmaceutical ingredient within our vitamins, excipients and other APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. It is used across pharmaceutical manufacturing.

We offer Disulfiram in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development
Nutraceutical & excipient use

Industries

Related to Disulfiram

View every impurity, metabolite and intermediate we list for Disulfiram.

Disulfiram impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Disulfiram
Catalogue No.	VQ-004236
CAS Number	97-77-8
IUPAC name	diethylcarbamothioylsulfanyl N,N-diethylcarbamodithioate
Molecular formula	C₁₀H₂₀N₂S₄
Molecular weight	296.5 g/mol
Exact mass	296.0509
Grade	IP/BP/USP
InChIKey	AUZONCFQVSMFAP-UHFFFAOYSA-N
SMILES	CCN(CC)C(=S)SSC(=S)N(CC)CC
PubChem CID	3117

Physical properties
Physical form	Powder
Appearance	White with yellowness greenish hue,to light yellow with greenish hue color crystalline powder(Results:Positive)
LogP (XLogP3)	3.9
H-bond donors / acceptors	0 / 4
TPSA	121 Å²
Synonyms	Tetraethylthiuram disulfide, Bis(diethylthiocarbamoyl) disulfide, Esperal, Alcophobin, Anticol, Abstinyl, Dicupral, Refusal, Teturamin, Ethyl Thiram, Antaethyl, Antalcol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P319, P321, P330, P333 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Disulfiram?

The CAS Registry Number of Disulfiram is 97-77-8. It is also known as Tetraethylthiuram disulfide, Bis(diethylthiocarbamoyl) disulfide, Esperal.

What is the molecular formula and molecular weight of Disulfiram?

Disulfiram has the molecular formula C10H20N2S4 and a molecular weight of 296.5 g/mol. Its IUPAC name is diethylcarbamothioylsulfanyl N,N-diethylcarbamodithioate.

What is Disulfiram used for?

Disulfiram is supplied as a characterised reference material related to Disulfiram. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Disulfiram can I order?

We supply Disulfiram in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Disulfiram?

Yes. Every lot of Disulfiram is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Disulfiram be shipped internationally?

Yes. Disulfiram is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.