10H-Phenothiazine 5,5-dioxide

Name: 10H-Phenothiazine 5,5-dioxide
Brand: Vaqora Chemicals
SKU: VQ-033150

About 10H-Phenothiazine 5,5-dioxide

10H-Phenothiazine 5,5-dioxide is an impurity of Promethazine carrying the CAS registry number 1209-66-1. With the molecular formula C12H9NO2S, it has a molar mass of 231.27 g/mol. Alternative names: Phenothiazine -dioxide and Phenothiazine 5,5-dioxide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Promethazine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 10H-Phenothiazine 5,5-dioxide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Promethazine

View every impurity, metabolite and intermediate we list for Promethazine.

Promethazine impurities

Specifications & identifiers

Chemical identifiers
Product name	10H-Phenothiazine 5,5-dioxide
Catalogue No.	VQ-033150
CAS Number	1209-66-1
IUPAC name	10H-phenothiazine 5,5-dioxide
Molecular formula	C₁₂H₉NO₂S
Molecular weight	231.27 g/mol
Exact mass	231.0354
Grade	Reference Standard
HSN code	38229090
InChIKey	ZAYUOSICZWFJSW-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)NC3=CC=CC=C3S2(=O)=O
PubChem CID	71024

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 3
TPSA	54.6 Å²
Synonyms	Phenothiazine -dioxide, Phenothiazine 5,5-dioxide, 5,5-Dioxophenothiazine, phenothiazine s,s-dioxide, 5,5-Dioxo-10H-phenothiazine, Phenothiazine dioxide, phenothiazine-s,s-dioxide, 10H-dibenzo[b,e]1,4-thiazine-5,5-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 10H-Phenothiazine 5,5-dioxide?

The CAS Registry Number of 10H-Phenothiazine 5,5-dioxide is 1209-66-1. It is also known as Phenothiazine -dioxide, Phenothiazine 5,5-dioxide, 5,5-Dioxophenothiazine.

What is the molecular formula and molecular weight of 10H-Phenothiazine 5,5-dioxide?

10H-Phenothiazine 5,5-dioxide has the molecular formula C12H9NO2S and a molecular weight of 231.27 g/mol. Its IUPAC name is 10H-phenothiazine 5,5-dioxide.

What is 10H-Phenothiazine 5,5-dioxide used for?

10H-Phenothiazine 5,5-dioxide is supplied as a characterised reference material related to Promethazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 10H-Phenothiazine 5,5-dioxide can I order?

We supply 10H-Phenothiazine 5,5-dioxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 10H-Phenothiazine 5,5-dioxide?

Yes. Every lot of 10H-Phenothiazine 5,5-dioxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 10H-Phenothiazine 5,5-dioxide be shipped internationally?

Yes. 10H-Phenothiazine 5,5-dioxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.