N-Nitroso-desmethyl Promethazine

Name: N-Nitroso-desmethyl Promethazine
Brand: Vaqora Chemicals
SKU: VQ-027650

About N-Nitroso-desmethyl Promethazine

N-Nitroso-desmethyl Promethazine is a nitrosamine impurity of Promethazine carrying the CAS registry number 94511-44-1. Formula C16H17N3OS, molecular weight 299.4 g/mol. Its systematic (IUPAC) name is N-methyl-N-(1-phenothiazin-10-ylpropan-2-yl)nitrous amide. It is also known as N-Desmethyl,-N-nitroso-promethazine or N-Nitrosodemethyl Promethazine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Promethazine, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Nitroso-desmethyl Promethazine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Promethazine

View every impurity, metabolite and intermediate we list for Promethazine.

Promethazine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-desmethyl Promethazine
Catalogue No.	VQ-027650
CAS Number	94511-44-1
IUPAC name	N-methyl-N-(1-phenothiazin-10-ylpropan-2-yl)nitrous amide
Molecular formula	C₁₆H₁₇N₃OS
Molecular weight	299.4 g/mol
Exact mass	299.1092
Grade	Reference Standard
HSN code	38229090
InChIKey	JIRNXXOVPUOGGK-UHFFFAOYSA-N
SMILES	CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)N=O
PubChem CID	171381101

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	0 / 5
TPSA	61.2 Å²
Synonyms	N-(1-(10H-Phenothiazin-10-yl)propan-2-yl)-N-methylnitrous Amide, N-Desmethyl,-N-nitroso-promethazine, N-Nitrosodemethyl Promethazine, N,alpha-Dimethyl-N-nitroso-10H-phenothiazine-10-ethanamine, 10H-Phenothiazine-10-ethanamine, N,alpha-dimethyl-N-nitroso-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-desmethyl Promethazine?

The CAS Registry Number of N-Nitroso-desmethyl Promethazine is 94511-44-1. It is also known as N-(1-(10H-Phenothiazin-10-yl)propan-2-yl)-N-methylnitrous Amide, N-Desmethyl,-N-nitroso-promethazine, N-Nitrosodemethyl Promethazine.

What is the molecular formula and molecular weight of N-Nitroso-desmethyl Promethazine?

N-Nitroso-desmethyl Promethazine has the molecular formula C16H17N3OS and a molecular weight of 299.4 g/mol. Its IUPAC name is N-methyl-N-(1-phenothiazin-10-ylpropan-2-yl)nitrous amide.

What is N-Nitroso-desmethyl Promethazine used for?

N-Nitroso-desmethyl Promethazine is supplied as a characterised reference material related to Promethazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-desmethyl Promethazine can I order?

We supply N-Nitroso-desmethyl Promethazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-desmethyl Promethazine?

Yes. Every lot of N-Nitroso-desmethyl Promethazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-desmethyl Promethazine be shipped internationally?

Yes. We export N-Nitroso-desmethyl Promethazine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.