2,4-Diaminopteridine

Name: 2,4-Diaminopteridine
Brand: Vaqora Chemicals
SKU: VQ-038360

About 2,4-Diaminopteridine

2,4-Diaminopteridine (CAS 1127-93-1) is an impurity of Methotrexate offered by Vaqora Chemicals. The compound has the formula C6H6N6, corresponding to a molecular weight of 162.15 g/mol. Systematically, it is named pteridine-2,4-diamine. Alternative names: 2,4-Pteridinediamine and 2,4-NH2-pteridine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Methotrexate impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	2,4-Diaminopteridine
Catalogue No.	VQ-038360
CAS Number	1127-93-1
IUPAC name	pteridine-2,4-diamine
Molecular formula	C₆H₆N₆
Molecular weight	162.15 g/mol
Exact mass	162.0654
Grade	Reference Standard
HSN code	38229090
InChIKey	CITCTUNIFJOTHI-UHFFFAOYSA-N
SMILES	C1=CN=C2C(=N1)C(=NC(=N2)N)N
PubChem CID	348669

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	2 / 6
TPSA	104 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,4-Diaminopteridine?

The CAS Registry Number of 2,4-Diaminopteridine is 1127-93-1. It is also known as 2,4-Pteridinediamine, 2,4-NH2-pteridine, Pteridine, 2,4-diamino-.

What is the molecular formula and molecular weight of 2,4-Diaminopteridine?

2,4-Diaminopteridine has the molecular formula C6H6N6 and a molecular weight of 162.15 g/mol. Its IUPAC name is pteridine-2,4-diamine.

What is 2,4-Diaminopteridine used for?

2,4-Diaminopteridine is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,4-Diaminopteridine can I order?

We supply 2,4-Diaminopteridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,4-Diaminopteridine?

Yes. Every lot of 2,4-Diaminopteridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,4-Diaminopteridine be shipped internationally?

Yes. 2,4-Diaminopteridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.