Diethyl (4-(dimethylamino)benzoyl)-L-glutamate 909874-43-7

Name: Diethyl (4-(dimethylamino)benzoyl)-L-glutamate
Brand: Vaqora Chemicals
SKU: VQ-038362

About Diethyl (4-(dimethylamino)benzoyl)-L-glutamate

Diethyl (4-(dimethylamino)benzoyl)-L-glutamate (CAS 909874-43-7) is an impurity of Methotrexate offered by Vaqora Chemicals. With the molecular formula C18H26N2O5, it has a molar mass of 350.4 g/mol. The IUPAC name is diethyl (2S)-2-[[4-(dimethylamino)benzoyl]amino]pentanedioate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Methotrexate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Diethyl (4-(dimethylamino)benzoyl)-L-glutamate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	Diethyl (4-(dimethylamino)benzoyl)-L-glutamate
Catalogue No.	VQ-038362
CAS Number	909874-43-7
IUPAC name	diethyl (2S)-2-[[4-(dimethylamino)benzoyl]amino]pentanedioate
Molecular formula	C₁₈H₂₆N₂O₅
Molecular weight	350.4 g/mol
Exact mass	350.1842
Grade	Reference Standard
HSN code	38229090
InChIKey	TVPVSPYFSWOXPF-HNNXBMFYSA-N
SMILES	CCOC(=O)CC[C@@H](C(=O)OCC)NC(=O)C1=CC=C(C=C1)N(C)C
PubChem CID	177828877

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 6
TPSA	84.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diethyl (4-(dimethylamino)benzoyl)-L-glutamate?

The CAS Registry Number of Diethyl (4-(dimethylamino)benzoyl)-L-glutamate is 909874-43-7. It is also known as N-[p-(Dimethylamino)benzoyl]-glutamic acid diethyl ester, Glutamic acid, N-[p-(dimethylamino)benzoyl]-, diethyl ester.

What is the molecular formula and molecular weight of Diethyl (4-(dimethylamino)benzoyl)-L-glutamate?

Diethyl (4-(dimethylamino)benzoyl)-L-glutamate has the molecular formula C18H26N2O5 and a molecular weight of 350.4 g/mol. Its IUPAC name is diethyl (2S)-2-[[4-(dimethylamino)benzoyl]amino]pentanedioate.

What is Diethyl (4-(dimethylamino)benzoyl)-L-glutamate used for?

Diethyl (4-(dimethylamino)benzoyl)-L-glutamate is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diethyl (4-(dimethylamino)benzoyl)-L-glutamate can I order?

We supply Diethyl (4-(dimethylamino)benzoyl)-L-glutamate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diethyl (4-(dimethylamino)benzoyl)-L-glutamate?

Yes. Every lot of Diethyl (4-(dimethylamino)benzoyl)-L-glutamate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diethyl (4-(dimethylamino)benzoyl)-L-glutamate be shipped internationally?

Yes. We export Diethyl (4-(dimethylamino)benzoyl)-L-glutamate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.