4-(Methylamino)benzoic acid

Name: 4-(Methylamino)benzoic acid
Brand: Vaqora Chemicals
SKU: VQ-038359

About 4-(Methylamino)benzoic acid

Listed under CAS 10541-83-0, 4-(Methylamino)benzoic acid is an impurity of Methotrexate available from Vaqora Chemicals. The compound has the formula C8H9NO2, corresponding to a molecular weight of 151.16 g/mol. Common synonyms include Benzoic acid, 4-(methylamino)- and N-Methyl-4-aminobenzoic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Methotrexate impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-(Methylamino)benzoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Methylamino)benzoic acid
Catalogue No.	VQ-038359
CAS Number	10541-83-0
IUPAC name	4-(methylamino)benzoic acid
Molecular formula	C₈H₉NO₂
Molecular weight	151.16 g/mol
Exact mass	151.0633
Grade	Reference Standard
HSN code	38229090
InChIKey	ZVIDMSBTYRSMAR-UHFFFAOYSA-N
SMILES	CNC1=CC=C(C=C1)C(=O)O
PubChem CID	66345

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 3
TPSA	49.3 Å²
Synonyms	Benzoic acid, 4-(methylamino)-, N-Methyl-4-aminobenzoic acid, 4-(N-Methylamino)benzoic acid, p-Methylaminobenzoic acid, Benzoic acid, p-(methylamino)-, N-Methyl-4-aminobenzoate, p-(Methylamino)benzoic acid, p-Carboxy-N-methylaniline, p-(N-Methylamino)benzoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Methylamino)benzoic acid?

The CAS Registry Number of 4-(Methylamino)benzoic acid is 10541-83-0. It is also known as Benzoic acid, 4-(methylamino)-, N-Methyl-4-aminobenzoic acid, 4-(N-Methylamino)benzoic acid.

What is the molecular formula and molecular weight of 4-(Methylamino)benzoic acid?

4-(Methylamino)benzoic acid has the molecular formula C8H9NO2 and a molecular weight of 151.16 g/mol. Its IUPAC name is 4-(methylamino)benzoic acid.

What is 4-(Methylamino)benzoic acid used for?

4-(Methylamino)benzoic acid is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Methylamino)benzoic acid can I order?

We supply 4-(Methylamino)benzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Methylamino)benzoic acid?

Yes. Every lot of 4-(Methylamino)benzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Methylamino)benzoic acid be shipped internationally?

Yes. 4-(Methylamino)benzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.