3-[(Aminoiminomethyl)amino]-4-methylbenzoic A… 641569-96-2

Name: 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate
Brand: Vaqora Chemicals
SKU: VQ-038640

About 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate

3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate is an impurity of Nilotinib carrying the CAS registry number 641569-96-2. Its molecular formula is C11H16N4O5 and its molecular weight is 284.27 g/mol. Common synonyms include Ethyl 3-guanidino-4-methylbenzoate nitrate and Ethyl 3-Carbamimidoylamino-p-toluate Nitrate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Nilotinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate
Catalogue No.	VQ-038640
CAS Number	641569-96-2
IUPAC name	ethyl 3-(diaminomethylideneamino)-4-methylbenzoate;nitric acid
Molecular formula	C₁₁H₁₆N₄O₅
Molecular weight	284.27 g/mol
Exact mass	284.1121
Grade	Reference Standard
HSN code	38229090
InChIKey	YQMZYKJPGMVZJL-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=CC(=C(C=C1)C)N=C(N)N.[N+](=O)(O)[O-]
PubChem CID	44181764

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 6
TPSA	157 Å²
Synonyms	Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate, Ethyl 3-guanidino-4-methylbenzoate nitrate, Ethyl 3-Carbamimidoylamino-p-toluate Nitrate, 3-Carbamimidoylamino-p-toluic Acid Ethyl Ester Nitrate, Nitric acid--ethyl 3-[(diaminomethylidene)amino]-4-methylbenzoate (1/1), Ethyl 3-[(Diaminomethylidene)amino]-4-methylbenzoate Nitrate, Ethyl3-guanidino-4-methylbenzoatenitrate, 3-guanidino-4-methylbenzoic acid ethyl ester nitrate, 3-Carbamimidoylamino-4-methylbenzoic Acid Ethyl Ester Nitrate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate?

The CAS Registry Number of 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate is 641569-96-2. It is also known as Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate, Ethyl 3-guanidino-4-methylbenzoate nitrate, Ethyl 3-Carbamimidoylamino-p-toluate Nitrate.

What is the molecular formula and molecular weight of 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate?

3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate has the molecular formula C11H16N4O5 and a molecular weight of 284.27 g/mol.

What is 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate used for?

3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate can I order?

We supply 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate?

Yes. Every lot of 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate be shipped internationally?

Yes. 3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.