Nilotinib Impurity A

Name: Nilotinib Impurity A
Brand: Vaqora Chemicals
SKU: VQ-038638

About Nilotinib Impurity A

Nilotinib Impurity A is an impurity of Nilotinib carrying the CAS registry number 1345336-53-9. The compound has the formula C20H19F3N6O, corresponding to a molecular weight of 416.4 g/mol. The IUPAC name is 3-(diaminomethylideneamino)-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide. Alternative names: Nilotinib Impurity 62.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Nilotinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nilotinib Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib Impurity A
Catalogue No.	VQ-038638
CAS Number	1345336-53-9
IUPAC name	3-(diaminomethylideneamino)-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide
Molecular formula	C₂₀H₁₉F₃N₆O
Molecular weight	416.4 g/mol
Exact mass	416.1572
Grade	Reference Standard
HSN code	38229090
InChIKey	PEQMCOFKBXMGDC-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)N=C(N)N
PubChem CID	73554931

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	3 / 6
TPSA	111 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib Impurity A?

The CAS Registry Number of Nilotinib Impurity A is 1345336-53-9. It is also known as 3-Guanidino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide, Nilotinib Impurity 62.

What is the molecular formula and molecular weight of Nilotinib Impurity A?

Nilotinib Impurity A has the molecular formula C20H19F3N6O and a molecular weight of 416.4 g/mol. Its IUPAC name is 3-(diaminomethylideneamino)-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide.

What is Nilotinib Impurity A used for?

Nilotinib Impurity A is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib Impurity A can I order?

We supply Nilotinib Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib Impurity A?

Yes. Every lot of Nilotinib Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib Impurity A be shipped internationally?

Yes. We export Nilotinib Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.