4-Amino-3,5-dichloropyridine

Name: 4-Amino-3,5-dichloropyridine
Brand: Vaqora Chemicals
SKU: VQ-013078

About 4-Amino-3,5-dichloropyridine

4-Amino-3,5-dichloropyridine (CAS 22889-78-7) is a process intermediate or related compound of Roflumilast offered by Vaqora Chemicals. Its molecular formula is C5H4Cl2N2 and its molecular weight is 163.0 g/mol. The IUPAC name is 3,5-dichloropyridin-4-amine. Alternative names: 3,5-Dichloro-4-pyridinamine and 3,5-Dichloro-4-aminopyridine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 8 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Roflumilast, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 4-Amino-3,5-dichloropyridine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Roflumilast

View every impurity, metabolite and intermediate we list for Roflumilast.

Roflumilast impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Amino-3,5-dichloropyridine
Catalogue No.	VQ-013078
CAS Number	22889-78-7
IUPAC name	3,5-dichloropyridin-4-amine
Molecular formula	C₅H₄Cl₂N₂
Molecular weight	163 g/mol
Exact mass	161.9752
Grade	Reference Standard
HSN code	2933
InChIKey	ISIQAMHROGZHOV-UHFFFAOYSA-N
SMILES	C1=C(C(=C(C=N1)Cl)N)Cl
PubChem CID	89888

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 2
TPSA	38.9 Å²
Synonyms	3,5-Dichloro-4-pyridinamine, 3,5-Dichloro-4-aminopyridine, 3,5-Dichloropyridin-4-ylamine, 3,5-Dichloropyridine-4-amine, 4-Amino-3,5-dichloropyridine, 4-Pyridinamine, 3,5-dichloro-, 3,5-Dichloro-4-pyridine amine, 3,5-dichloro-4-amino pyridine, 4-amino-3,5-dichloro pyridine, 3,5-dichloro-4-pyridylamine, 4-amino3,5-dichloropyridine

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H302Harmful if swallowed
H310Fatal in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H330Fatal if inhaled
H335May cause respiratory irritation

Precautionary statements: P260, P261, P262, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P319, P320, P321, P330, P332 + P317, P337 + P317, P361 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Amino-3,5-dichloropyridine?

The CAS Registry Number of 4-Amino-3,5-dichloropyridine is 22889-78-7. It is also known as 3,5-Dichloro-4-pyridinamine, 3,5-Dichloro-4-aminopyridine, 3,5-Dichloropyridin-4-ylamine.

What is the molecular formula and molecular weight of 4-Amino-3,5-dichloropyridine?

4-Amino-3,5-dichloropyridine has the molecular formula C5H4Cl2N2 and a molecular weight of 163 g/mol. Its IUPAC name is 3,5-dichloropyridin-4-amine.

What is 4-Amino-3,5-dichloropyridine used for?

4-Amino-3,5-dichloropyridine is supplied as a characterised reference material related to Roflumilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-3,5-dichloropyridine can I order?

We supply 4-Amino-3,5-dichloropyridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-3,5-dichloropyridine?

Yes. Every lot of 4-Amino-3,5-dichloropyridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-3,5-dichloropyridine be shipped internationally?

Yes. 4-Amino-3,5-dichloropyridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.