Cabozantinib Hydroxy Impurity

Name: Cabozantinib Hydroxy Impurity
Brand: Vaqora Chemicals
SKU: VQ-004574

About Cabozantinib Hydroxy Impurity

Listed under CAS 849217-60-3, Cabozantinib Hydroxy Impurity is an impurity of Cabozantinib available from Vaqora Chemicals. Formula C17H15FN2O3, molecular weight 314.31 g/mol. The IUPAC name is 1-N'-(4-fluorophenyl)-1-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide. Alternative names: Cabozantinib Impurity 28 and N-(4-Fluoropheny.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Cabozantinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Cabozantinib Hydroxy Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cabozantinib

View every impurity, metabolite and intermediate we list for Cabozantinib.

Cabozantinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Cabozantinib Hydroxy Impurity
Catalogue No.	VQ-004574
CAS Number	849217-60-3
IUPAC name	1-N'-(4-fluorophenyl)-1-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
Molecular formula	C₁₇H₁₅FN₂O₃
Molecular weight	314.31 g/mol
Exact mass	314.1067
Grade	Reference Standard
HSN code	38229090
InChIKey	FSFMBVMXIPQPMJ-UHFFFAOYSA-N
SMILES	C1CC1(C(=O)NC2=CC=C(C=C2)O)C(=O)NC3=CC=C(C=C3)F
PubChem CID	57810197

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	3 / 4
TPSA	78.4 Å²
Synonyms	N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide, N-(4-Fluorophenyl)-N′-(4-hydroxyphenyl)-1,1-cyclopropanedicarboxamide, 1-N′-(4-Fluorophenyl)-1-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide, N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide, Cabozantinib Impurity 28, N'1-(4-fluorophenyl)-N1-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide, N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)-1,1-cyclopropanedicarboxamide, 1,1-Cyclopropanedicarboxamide, N-(4-fluorophenyl)-N'-(4-hydroxyphenyl)-, N-(4-Fluoropheny, CS-M3495, N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)-cyclopropane-1,1-dicarboxamide, N1'-(4-fluorophenyl)-N1-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cabozantinib Hydroxy Impurity?

The CAS Registry Number of Cabozantinib Hydroxy Impurity is 849217-60-3. It is also known as N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide, N-(4-Fluorophenyl)-N′-(4-hydroxyphenyl)-1,1-cyclopropanedicarboxamide, 1-N′-(4-Fluorophenyl)-1-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide.

What is the molecular formula and molecular weight of Cabozantinib Hydroxy Impurity?

Cabozantinib Hydroxy Impurity has the molecular formula C17H15FN2O3 and a molecular weight of 314.31 g/mol. Its IUPAC name is 1-N'-(4-fluorophenyl)-1-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide.

What is Cabozantinib Hydroxy Impurity used for?

Cabozantinib Hydroxy Impurity is supplied as a characterised reference material related to Cabozantinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cabozantinib Hydroxy Impurity can I order?

We supply Cabozantinib Hydroxy Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cabozantinib Hydroxy Impurity?

Yes. Every lot of Cabozantinib Hydroxy Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cabozantinib Hydroxy Impurity be shipped internationally?

Yes. Cabozantinib Hydroxy Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.