4-Chloro-6,7-dimethoxyquinoline

Name: 4-Chloro-6,7-dimethoxyquinoline
Brand: Vaqora Chemicals
SKU: VQ-013096

About 4-Chloro-6,7-dimethoxyquinoline

Listed under CAS 35654-56-9, 4-Chloro-6,7-dimethoxyquinoline is a process intermediate or related compound of Cabozantinib available from Vaqora Chemicals. With the molecular formula C11H10ClNO2, it has a molar mass of 223.65 g/mol. It is also known as 4-Chloro-6,7-dimethoxy-quinoline or 6,7-Dimethoxy-4-chloroquinoline.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Cabozantinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 4-Chloro-6,7-dimethoxyquinoline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Cabozantinib

View every impurity, metabolite and intermediate we list for Cabozantinib.

Cabozantinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloro-6,7-dimethoxyquinoline
Catalogue No.	VQ-013096
CAS Number	35654-56-9
IUPAC name	4-chloro-6,7-dimethoxyquinoline
Molecular formula	C₁₁H₁₀ClNO₂
Molecular weight	223.65 g/mol
Exact mass	223.04
Grade	Reference Standard
HSN code	2933
InChIKey	WRVHQEYBCDPZEU-UHFFFAOYSA-N
SMILES	COC1=CC2=C(C=CN=C2C=C1OC)Cl
PubChem CID	459610

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 3
TPSA	31.4 Å²
Synonyms	4-Chloro-6,7-dimethoxy-quinoline, 6,7-Dimethoxy-4-chloroquinoline, 4-chloro-6,7-dimethoxy quinoline, -Chloro-6,7-dimethoxyquinoline, 4Chloro-6,7-dimethoxy-quinoline, 4-chloro-6,7-dimethoxyquinoline, AldrichCPR, 6,7-Dimethoxy-4-chloroquinoline pound>>4-Chloro-6,7-dimethoxy-quino

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloro-6,7-dimethoxyquinoline?

The CAS Registry Number of 4-Chloro-6,7-dimethoxyquinoline is 35654-56-9. It is also known as 4-Chloro-6,7-dimethoxy-quinoline, 6,7-Dimethoxy-4-chloroquinoline, 4-chloro-6,7-dimethoxy quinoline.

What is the molecular formula and molecular weight of 4-Chloro-6,7-dimethoxyquinoline?

4-Chloro-6,7-dimethoxyquinoline has the molecular formula C11H10ClNO2 and a molecular weight of 223.65 g/mol. Its IUPAC name is 4-chloro-6,7-dimethoxyquinoline.

What is 4-Chloro-6,7-dimethoxyquinoline used for?

4-Chloro-6,7-dimethoxyquinoline is supplied as a characterised reference material related to Cabozantinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloro-6,7-dimethoxyquinoline can I order?

We supply 4-Chloro-6,7-dimethoxyquinoline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloro-6,7-dimethoxyquinoline?

Yes. Every lot of 4-Chloro-6,7-dimethoxyquinoline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloro-6,7-dimethoxyquinoline be shipped internationally?

Yes. 4-Chloro-6,7-dimethoxyquinoline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.