Cabozantinib N-Oxide
Synonyms: Cabozantinib metabolite M19 · EXEL-5162 · US10273211, Compound 19
Cabozantinib N-Oxide (CAS 1621681-63-7) – Cabozantinib impurity standard, 98.28%. C28H24FN3O6, MW 517.5. Vaqora Chemicals: COA, global shipping.
About Cabozantinib N-Oxide
Vaqora Chemicals supplies Cabozantinib N-Oxide, a metabolite or degradation product of Cabozantinib registered under CAS number 1621681-63-7, specified at 98.28% purity. Its molecular formula is C28H24FN3O6 and its molecular weight is 517.5 g/mol. Alternative names: Cabozantinib metabolite M19 and EXEL-5162.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.
Analytical teams use this compound to identify metabolites and degradants of Cabozantinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
We offer Cabozantinib N-Oxide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Industries
View every impurity, metabolite and intermediate we list for Cabozantinib.
Cabozantinib impuritiesSpecifications & identifiers
| Product name | Cabozantinib N-Oxide |
|---|---|
| Catalogue No. | VQ-007112 |
| CAS Number | 1621681-63-7 |
| IUPAC name | 1-N-[4-(6,7-dimethoxy-1-oxidoquinolin-1-ium-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
| Molecular formula | C28H24FN3O6 |
| Molecular weight | 517.5 g/mol |
| Exact mass | 517.1649 |
| Grade | Reference Standard |
| Purity / assay | 98.28% |
| HSN code | 38229090 |
| InChIKey | FKJJTKYQXXLFPS-UHFFFAOYSA-N |
| SMILES | COC1=CC2=C(C=C[N+](=C2C=C1OC)[O-])OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F |
| PubChem CID | 78325042 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 4.4 |
| H-bond donors / acceptors | 2 / 7 |
| TPSA | 111 Ų |
Documents
Frequently asked questions
What is the CAS number of Cabozantinib N-Oxide?
The CAS Registry Number of Cabozantinib N-Oxide is 1621681-63-7. It is also known as Cabozantinib metabolite M19, EXEL-5162, US10273211, Compound 19.
What is the molecular formula and molecular weight of Cabozantinib N-Oxide?
Cabozantinib N-Oxide has the molecular formula C28H24FN3O6 and a molecular weight of 517.5 g/mol. Its IUPAC name is 1-N-[4-(6,7-dimethoxy-1-oxidoquinolin-1-ium-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide.
What is Cabozantinib N-Oxide used for?
Cabozantinib N-Oxide is supplied as a characterised reference material related to Cabozantinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Cabozantinib N-Oxide can I order?
We supply Cabozantinib N-Oxide in Reference Standard (98.28%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Cabozantinib N-Oxide?
Yes. Every lot of Cabozantinib N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Cabozantinib N-Oxide be shipped internationally?
Yes. We export Cabozantinib N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about Cabozantinib N-Oxide
We reply within one business day with price, pack options, lead time and documentation.