Cabozantinib Impurity 1
Synonyms: Cabozantinib Amine Analog · 4-[(6,7-Dimethoxy-4-quinolinyl)oxy]benzenamine · 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline · 6,7-Dimethoxy-4-(4-aminophenoxy)quinoline
Cabozantinib Impurity 1 (CAS 190728-25-7) – Cabozantinib impurity standard. C17H16N2O3, MW 296.32. Supplied by Vaqora Chemicals with COA, exported worldwide.
About Cabozantinib Impurity 1
Cabozantinib Impurity 1 is an impurity of Cabozantinib carrying the CAS registry number 190728-25-7. Its molecular formula is C17H16N2O3 and its molecular weight is 296.32 g/mol. Systematically, it is named 4-(6,7-dimethoxyquinolin-4-yl)oxyaniline. It is also known as Cabozantinib Amine Analog or 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline.
The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.
As a characterised impurity of Cabozantinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cabozantinib Impurity 1 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Cabozantinib.
Cabozantinib impuritiesSpecifications & identifiers
| Product name | Cabozantinib Impurity 1 |
|---|---|
| Catalogue No. | VQ-004575 |
| CAS Number | 190728-25-7 |
| IUPAC name | 4-(6,7-dimethoxyquinolin-4-yl)oxyaniline |
| Molecular formula | C17H16N2O3 |
| Molecular weight | 296.32 g/mol |
| Exact mass | 296.1161 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | VXEQRXJATQUJSN-UHFFFAOYSA-N |
| SMILES | COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)N |
| PubChem CID | 11594543 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 3 |
| H-bond donors / acceptors | 1 / 5 |
| TPSA | 66.6 Ų |
| Synonyms | Cabozantinib Amine Analog, 4-[(6,7-Dimethoxy-4-quinolinyl)oxy]benzenamine, 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline, 6,7-Dimethoxy-4-(4-aminophenoxy)quinoline, [4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]amine Cabozantinib Amine Analog, 4-[(6,7-dimethoxyquinolin-4-yl)oxy]aniline, Benzenamine, 4-[(6,7-dimethoxy-4-quinolinyl)oxy]-, 4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline, 4-(4-Aminophenoxy)-6,7-dimethoxyquinoline, 4-(6,7-dimethoxyquinolin-4-yloxy)phenylamine, 4-(6,7-dimethoxyquinolin-4-yloxy)aniline, 4-(6,7-Dimethoxy-4-quinolyloxy)aniline |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H315Causes skin irritationH319Causes serious eye irritation
Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Cabozantinib Impurity 1?
The CAS Registry Number of Cabozantinib Impurity 1 is 190728-25-7. It is also known as Cabozantinib Amine Analog, 4-[(6,7-Dimethoxy-4-quinolinyl)oxy]benzenamine, 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline.
What is the molecular formula and molecular weight of Cabozantinib Impurity 1?
Cabozantinib Impurity 1 has the molecular formula C17H16N2O3 and a molecular weight of 296.32 g/mol. Its IUPAC name is 4-(6,7-dimethoxyquinolin-4-yl)oxyaniline.
What is Cabozantinib Impurity 1 used for?
Cabozantinib Impurity 1 is supplied as a characterised reference material related to Cabozantinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Cabozantinib Impurity 1 can I order?
We supply Cabozantinib Impurity 1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Cabozantinib Impurity 1?
Yes. Every lot of Cabozantinib Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Cabozantinib Impurity 1 be shipped internationally?
Yes. Cabozantinib Impurity 1 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Cabozantinib Impurity 1
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