Diethyl (4-hydroxybenzoyl)-L-glutamate

Name: Diethyl (4-hydroxybenzoyl)-L-glutamate
Brand: Vaqora Chemicals
SKU: VQ-031832

About Diethyl (4-hydroxybenzoyl)-L-glutamate

Listed under CAS 57963-63-0, Diethyl (4-hydroxybenzoyl)-L-glutamate is a metabolite or degradation product of Methotrexate available from Vaqora Chemicals. Formula C16H21NO6, molecular weight 323.34 g/mol. The IUPAC name is diethyl (2S)-2-[(4-hydroxybenzoyl)amino]pentanedioate. Alternative names: 1,5-Diethyl N-(4-hydroxybenzoyl)-L-glutamate and Diethyl N-(4-hydroxybenzoyl)-L-glutamate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Methotrexate, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Diethyl (4-hydroxybenzoyl)-L-glutamate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	Diethyl (4-hydroxybenzoyl)-L-glutamate
Catalogue No.	VQ-031832
CAS Number	57963-63-0
IUPAC name	diethyl (2S)-2-[(4-hydroxybenzoyl)amino]pentanedioate
Molecular formula	C₁₆H₂₁NO₆
Molecular weight	323.34 g/mol
Exact mass	323.1369
Grade	Reference Standard
HSN code	38229090
InChIKey	QFXWYXFNNKEAHM-ZDUSSCGKSA-N
SMILES	CCOC(=O)CC[C@@H](C(=O)OCC)NC(=O)C1=CC=C(C=C1)O
PubChem CID	54226042

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	2 / 6
TPSA	102 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diethyl (4-hydroxybenzoyl)-L-glutamate?

The CAS Registry Number of Diethyl (4-hydroxybenzoyl)-L-glutamate is 57963-63-0. It is also known as 1,5-Diethyl N-(4-hydroxybenzoyl)-L-glutamate, Diethyl N-(4-hydroxybenzoyl)-L-glutamate.

What is the molecular formula and molecular weight of Diethyl (4-hydroxybenzoyl)-L-glutamate?

Diethyl (4-hydroxybenzoyl)-L-glutamate has the molecular formula C16H21NO6 and a molecular weight of 323.34 g/mol. Its IUPAC name is diethyl (2S)-2-[(4-hydroxybenzoyl)amino]pentanedioate.

What is Diethyl (4-hydroxybenzoyl)-L-glutamate used for?

Diethyl (4-hydroxybenzoyl)-L-glutamate is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diethyl (4-hydroxybenzoyl)-L-glutamate can I order?

We supply Diethyl (4-hydroxybenzoyl)-L-glutamate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diethyl (4-hydroxybenzoyl)-L-glutamate?

Yes. Every lot of Diethyl (4-hydroxybenzoyl)-L-glutamate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diethyl (4-hydroxybenzoyl)-L-glutamate be shipped internationally?

Yes. We export Diethyl (4-hydroxybenzoyl)-L-glutamate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.