Methotrexate EP Impurity B (MonoHydrate)

Name: Methotrexate EP Impurity B (MonoHydrate)
Brand: Vaqora Chemicals
SKU: VQ-031829

About Methotrexate EP Impurity B (MonoHydrate)

Methotrexate EP Impurity B (MonoHydrate) is a pharmacopeial impurity of Methotrexate carrying the CAS registry number 1217459-90-9. Its molecular formula is C19H22N8O6 and its molecular weight is 458.4 g/mol. It is also known as Methotrexate EP Impurity B Hydrate or Methotrexate Hydrate EP Impurity B.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Methotrexate impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Methotrexate EP Impurity B (MonoHydrate) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Methotrexate EP Impurity B (MonoHydrate)
Catalogue No.	VQ-031829
CAS Number	1217459-90-9
IUPAC name	2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid;hydrate
Molecular formula	C₁₉H₂₂N₈O₆
Molecular weight	458.4 g/mol
Exact mass	458.1662
Grade	Reference Standard
HSN code	38229090
InChIKey	UCQHQSNBTVOVLR-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N.O
PubChem CID	45157549

Physical properties
Physical form	Solid
H-bond donors / acceptors	7 / 13
TPSA	220 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methotrexate EP Impurity B (MonoHydrate)?

The CAS Registry Number of Methotrexate EP Impurity B (MonoHydrate) is 1217459-90-9. It is also known as Methotrexate EP Impurity B Hydrate, Methotrexate Hydrate EP Impurity B, (4-(((2,4-Diaminopteridin-6-yl)methyl)amino)benzoyl)glutamic acid hydrate.

What is the molecular formula and molecular weight of Methotrexate EP Impurity B (MonoHydrate)?

Methotrexate EP Impurity B (MonoHydrate) has the molecular formula C19H22N8O6 and a molecular weight of 458.4 g/mol.

What is Methotrexate EP Impurity B (MonoHydrate) used for?

Methotrexate EP Impurity B (MonoHydrate) is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methotrexate EP Impurity B (MonoHydrate) can I order?

We supply Methotrexate EP Impurity B (MonoHydrate) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methotrexate EP Impurity B (MonoHydrate)?

Yes. Every lot of Methotrexate EP Impurity B (MonoHydrate) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methotrexate EP Impurity B (MonoHydrate) be shipped internationally?

Yes. We export Methotrexate EP Impurity B (MonoHydrate) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.