N-(4-Chlorobenzoyl)-L-glutamic acid

Name: N-(4-Chlorobenzoyl)-L-glutamic acid
Brand: Vaqora Chemicals
SKU: VQ-031827

About N-(4-Chlorobenzoyl)-L-glutamic acid

Listed under CAS 57444-70-9, N-(4-Chlorobenzoyl)-L-glutamic acid is an impurity of Methotrexate available from Vaqora Chemicals. The compound has the formula C12H12ClNO5, corresponding to a molecular weight of 285.68 g/mol. The IUPAC name is 2-[(4-chlorobenzoyl)amino]pentanedioic acid. It is also known as (4-Chlorobenzoyl)-L-glutamic Acid or n-(4-chlorobenzoyl)glutamic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Methotrexate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-(4-Chlorobenzoyl)-L-glutamic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(4-Chlorobenzoyl)-L-glutamic acid
Catalogue No.	VQ-031827
CAS Number	57444-70-9
IUPAC name	2-[(4-chlorobenzoyl)amino]pentanedioic acid
Molecular formula	C₁₂H₁₂ClNO₅
Molecular weight	285.68 g/mol
Exact mass	285.0404
Grade	Reference Standard
HSN code	38229090
InChIKey	ZPXCXBRPCFSCHI-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)Cl
PubChem CID	93671

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	3 / 5
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(4-Chlorobenzoyl)-L-glutamic acid?

The CAS Registry Number of N-(4-Chlorobenzoyl)-L-glutamic acid is 57444-70-9. It is also known as (4-Chlorobenzoyl)-L-glutamic Acid, n-(4-chlorobenzoyl)glutamic acid, CBKinase1_000642.

What is the molecular formula and molecular weight of N-(4-Chlorobenzoyl)-L-glutamic acid?

N-(4-Chlorobenzoyl)-L-glutamic acid has the molecular formula C12H12ClNO5 and a molecular weight of 285.68 g/mol. Its IUPAC name is 2-[(4-chlorobenzoyl)amino]pentanedioic acid.

What is N-(4-Chlorobenzoyl)-L-glutamic acid used for?

N-(4-Chlorobenzoyl)-L-glutamic acid is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(4-Chlorobenzoyl)-L-glutamic acid can I order?

We supply N-(4-Chlorobenzoyl)-L-glutamic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(4-Chlorobenzoyl)-L-glutamic acid?

Yes. Every lot of N-(4-Chlorobenzoyl)-L-glutamic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(4-Chlorobenzoyl)-L-glutamic acid be shipped internationally?

Yes. We export N-(4-Chlorobenzoyl)-L-glutamic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.