Drospirenone

Name: Drospirenone
Brand: Vaqora Chemicals
SKU: VQ-004125

About Drospirenone

Vaqora Chemicals supplies Drospirenone (IP/BP/USP grade), a metabolic / hormonal API registered under CAS number 67392-87-4. With the molecular formula C24H30O3, it has a molar mass of 366.5 g/mol. Common synonyms include 6b,7b and dihydrospirorenone.

It is supplied as a powder. Store in a tightly closed container in a cool, dry and well-ventilated place. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This API belongs to our antidiabetic, hormone and metabolic APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Buyers come mainly from pharmaceutical manufacturing.

Standard pack sizes are 1 kg, 5 kg and 25 kg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Drospirenone
Catalogue No.	VQ-004125
CAS Number	67392-87-4
IUPAC name	(1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.02,4.05,10.014,19.016,18]nonadec-5-ene-15,5'-oxolane]-2',7-dione
Molecular formula	C₂₄H₃₀O₃
Molecular weight	366.5 g/mol
Exact mass	366.2195
Grade	IP/BP/USP
InChIKey	METQSPRSQINEEU-HXCATZOESA-N
SMILES	C[C@]12CCC(=O)C=C1[C@@H]3C[C@@H]3[C@@H]4[C@@H]2CC[C@]5([C@H]4[C@@H]6C[C@@H]6[C@@]57CCC(=O)O7)C
PubChem CID	68873

Physical properties
Physical form	Powder
LogP (XLogP3)	3.5
H-bond donors / acceptors	0 / 3
TPSA	43.4 Å²
Synonyms	6b,7b, 15b,16b-dimethylen-3-oxo-17a-pregn-4-ene- 21,17-carbolactone, dihydrospirorenone, Dehydrospirorenone, 1,2-Dihydrospirorenone, 1,2-dihydro-spirorenone, 6beta,7beta,15beta,16beta-dimethylen-3-oxo-17alpha-pregn-4-en-21,17-carbolacton, 6-beta,7-beta:15-beta,16-beta-Dimethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactone, Drospirenone CRS, SH-470, Slinda (TN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P263, P264, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Drospirenone?

The CAS Registry Number of Drospirenone is 67392-87-4. It is also known as 6b,7b, 15b,16b-dimethylen-3-oxo-17a-pregn-4-ene- 21,17-carbolactone, dihydrospirorenone.

What is the molecular formula and molecular weight of Drospirenone?

Drospirenone has the molecular formula C24H30O3 and a molecular weight of 366.5 g/mol. Its IUPAC name is (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.02,4.05,10.014,19.016,18]nonadec-5-ene-15,5'-oxolane]-2',7-dione.

Which grade and pack sizes of Drospirenone can I order?

We supply Drospirenone in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Drospirenone?

Yes. Every lot of Drospirenone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Drospirenone be shipped internationally?

Yes. Drospirenone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.