Levothyroxine EP Impurity B

Name: Levothyroxine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-034854

About Levothyroxine EP Impurity B

Levothyroxine EP Impurity B (CAS 1628720-66-0) is a pharmacopeial impurity of Levothyroxine offered by Vaqora Chemicals. The compound has the formula C15H11ClI3NO4, corresponding to a molecular weight of 685.42 g/mol. Systematically, it is named (2S)-2-amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl]propanoic acid. Common synonyms include Levothyroxine - Impurity B and 3-Chloro Thyroxine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Levothyroxine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Levothyroxine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine EP Impurity B
Catalogue No.	VQ-034854
CAS Number	1628720-66-0
IUPAC name	(2S)-2-amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl]propanoic acid
Molecular formula	C₁₅H₁₁ClI₃NO₄
Molecular weight	685.42 g/mol
Exact mass	684.7511
Grade	Reference Standard
HSN code	38229090
InChIKey	MQUDMFHNJQNOJT-LBPRGKRZSA-N
SMILES	C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)Cl)I)C[C@@H](C(=O)O)N
PubChem CID	54086387

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	3 / 5
TPSA	92.8 Å²
Synonyms	Levothyroxine - Impurity B, 3-Chloro Thyroxine, (2S)-2-amino-3-(4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl)propanoic acid, (2S)-2-Amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl] propanoic acid, (S)-2-Amino-3-(4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl)propanoic acid, 3-ChloroThyroxine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine EP Impurity B?

The CAS Registry Number of Levothyroxine EP Impurity B is 1628720-66-0. It is also known as Levothyroxine - Impurity B, 3-Chloro Thyroxine, (2S)-2-amino-3-(4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl)propanoic acid.

What is the molecular formula and molecular weight of Levothyroxine EP Impurity B?

Levothyroxine EP Impurity B has the molecular formula C15H11ClI3NO4 and a molecular weight of 685.42 g/mol. Its IUPAC name is (2S)-2-amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl]propanoic acid.

What is Levothyroxine EP Impurity B used for?

Levothyroxine EP Impurity B is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine EP Impurity B can I order?

We supply Levothyroxine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine EP Impurity B?

Yes. Every lot of Levothyroxine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine EP Impurity B be shipped internationally?

Yes. We export Levothyroxine EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.