Levothyroxine EP Impurity J

Name: Levothyroxine EP Impurity J
Brand: Vaqora Chemicals
SKU: VQ-034855

About Levothyroxine EP Impurity J

Vaqora Chemicals supplies Levothyroxine EP Impurity J, a pharmacopeial impurity of Levothyroxine registered under CAS number 4604-41-5. Its molecular formula is C15H13I2NO4 and its molecular weight is 525.08 g/mol. Systematically, it is named (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid. Alternative names: Levothyroxine - Impurity J and 3,3'-Diiodo-L-thyronine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Levothyroxine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Levothyroxine EP Impurity J in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine EP Impurity J
Catalogue No.	VQ-034855
CAS Number	4604-41-5
IUPAC name	(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
Molecular formula	C₁₅H₁₃I₂NO₄
Molecular weight	525.08 g/mol
Exact mass	524.8934
Grade	Reference Standard
HSN code	38229090
InChIKey	CPCJBZABTUOGNM-LBPRGKRZSA-N
SMILES	C1=CC(=C(C=C1C[C@@H](C(=O)O)N)I)OC2=CC(=C(C=C2)O)I
PubChem CID	107564

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	3 / 5
TPSA	92.8 Å²
Synonyms	Levothyroxine - Impurity J, 3,3'-Diiodo-L-thyronine, O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine, L-3,3'-Diiodothyronine, 3,3'-Diiodothyronine, L-, L-tyrosine, O-(4-hydroxy-3-iodophenyl)-3-iodo-, (2S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl)propanoate, (2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoate, (2S)-2-azaniumyl-3-(4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl)propanoate, (2S)-2-azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoate, (S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl)propanoic acid, 3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]-L-alanine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine EP Impurity J?

The CAS Registry Number of Levothyroxine EP Impurity J is 4604-41-5. It is also known as Levothyroxine - Impurity J, 3,3'-Diiodo-L-thyronine, O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine.

What is the molecular formula and molecular weight of Levothyroxine EP Impurity J?

Levothyroxine EP Impurity J has the molecular formula C15H13I2NO4 and a molecular weight of 525.08 g/mol. Its IUPAC name is (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid.

What is Levothyroxine EP Impurity J used for?

Levothyroxine EP Impurity J is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine EP Impurity J can I order?

We supply Levothyroxine EP Impurity J in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine EP Impurity J?

Yes. Every lot of Levothyroxine EP Impurity J is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine EP Impurity J be shipped internationally?

Yes. Levothyroxine EP Impurity J is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.