Loratadine

Name: Loratadine
Brand: Vaqora Chemicals
SKU: VQ-004176

About Loratadine

Vaqora Chemicals supplies Loratadine (IP/BP/USP grade), a respiratory / antiallergic API registered under CAS number 79794-75-5. The compound has the formula C22H23ClN2O2, corresponding to a molecular weight of 382.9 g/mol. Alternative names: Claritin and Clarityne.

It is supplied as a powder. Store in a tightly closed container in a cool, dry and well-ventilated place. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our respiratory and antiallergic APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Buyers come mainly from pharmaceutical manufacturing.

Standard pack sizes are 1 kg, 5 kg and 25 kg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Loratadine

View every impurity, metabolite and intermediate we list for Loratadine.

Loratadine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loratadine
Catalogue No.	VQ-004176
CAS Number	79794-75-5
IUPAC name	ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Molecular formula	C₂₂H₂₃ClN₂O₂
Molecular weight	382.9 g/mol
Exact mass	382.1448
Grade	IP/BP/USP
HSN code	2933
InChIKey	JCCNYMKQOSZNPW-UHFFFAOYSA-N
SMILES	CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1
PubChem CID	3957

Physical properties
Physical form	Powder
LogP (XLogP3)	5.2
H-bond donors / acceptors	0 / 3
TPSA	42.4 Å²
Synonyms	Claritin, Clarityne, Fristamin, Claritine, Lertamine, Lorastine, Loratyne, Claritin Reditabs, Claratyne, Loritine, Restamine, Loratadine Redidose

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P271, P272, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 79794-75-5

Reference Standard

Loratadine

CAS: 79794-75-5
Formula: C₂₂H₂₃ClN₂O₂
MW: 382.9 g/mol

In stock

Frequently asked questions

What is the CAS number of Loratadine?

The CAS Registry Number of Loratadine is 79794-75-5. It is also known as Claritin, Clarityne, Fristamin.

What is the molecular formula and molecular weight of Loratadine?

Loratadine has the molecular formula C22H23ClN2O2 and a molecular weight of 382.9 g/mol. Its IUPAC name is ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate.

What is Loratadine used for?

Loratadine is supplied as a characterised reference material related to Loratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loratadine can I order?

We supply Loratadine in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loratadine?

Yes. Every lot of Loratadine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loratadine be shipped internationally?

Yes. Loratadine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.