Macitentan ACT-373898

Name: Macitentan ACT-373898
Brand: Vaqora Chemicals
SKU: VQ-026550

About Macitentan ACT-373898

Vaqora Chemicals supplies Macitentan ACT-373898, an impurity of Macitentan registered under CAS number 1433875-14-9. The compound has the formula C15H17BrN4O5S, corresponding to a molecular weight of 445.3 g/mol. The IUPAC name is 2-[5-(4-bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyacetic acid. Common synonyms include Macitentan metabolite M5.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Macitentan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Macitentan ACT-373898 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Macitentan ACT-373898
Catalogue No.	VQ-026550
CAS Number	1433875-14-9
IUPAC name	2-[5-(4-bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyacetic acid
Molecular formula	C₁₅H₁₇BrN₄O₅S
Molecular weight	445.3 g/mol
Exact mass	444.0103
Grade	Reference Standard
HSN code	38229090
InChIKey	IMSGHDWVBCDHNU-UHFFFAOYSA-N
SMILES	CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCC(=O)O)C2=CC=C(C=C2)Br
PubChem CID	129011924

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	3 / 9
TPSA	139 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Macitentan ACT-373898?

The CAS Registry Number of Macitentan ACT-373898 is 1433875-14-9. It is also known as Macitentan metabolite M5, Acetic acid, 2-((5-(4-bromophenyl)-6-(((propylamino)sulfonyl)amino)-4-pyrimidinyl)oxy)-, 2-((5-(4-bromophenyl)-6-((N-propylsulfamoyl)amino)pyrimidin-4-yl)oxy)acetic acid.

What is the molecular formula and molecular weight of Macitentan ACT-373898?

Macitentan ACT-373898 has the molecular formula C15H17BrN4O5S and a molecular weight of 445.3 g/mol. Its IUPAC name is 2-[5-(4-bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyacetic acid.

What is Macitentan ACT-373898 used for?

Macitentan ACT-373898 is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Macitentan ACT-373898 can I order?

We supply Macitentan ACT-373898 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Macitentan ACT-373898?

Yes. Every lot of Macitentan ACT-373898 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Macitentan ACT-373898 be shipped internationally?

Yes. We export Macitentan ACT-373898 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.