Meclizine HCl

Name: Meclizine HCl
Brand: Vaqora Chemicals
SKU: VQ-004177

About Meclizine HCl

Listed under CAS 1104-22-9, Meclizine HCl is a respiratory / antiallergic API available from Vaqora Chemicals in IP/BP/USP grade, specified at ≥98.0% purity. Formula C25H29Cl3N2, molecular weight 463.9 g/mol. The IUPAC name is 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine. Dihydrochloride. It is also known as Meclozine dihydrochloride or Meclizine dihydrochloride.

The material typically appears as a yellow crystalline powder,odorless (Results:Conforms). Store in a tightly closed container in a cool, dry and well-ventilated place. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our respiratory and antiallergic APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. It is used across pharmaceutical manufacturing.

Vaqora Chemicals supplies Meclizine HCl in 1 kg, 5 kg and 25 kg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Meclizine

View every impurity, metabolite and intermediate we list for Meclizine.

Meclizine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Meclizine HCl
Catalogue No.	VQ-004177
CAS Number	1104-22-9
IUPAC name	1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;dihydrochloride
Molecular formula	C₂₅H₂₉Cl₃N₂
Molecular weight	463.9 g/mol
Exact mass	462.1396
Grade	IP/BP/USP
Purity / assay	≥98.0%
HSN code	2933
InChIKey	VCTHNOIYJIXQLV-UHFFFAOYSA-N
SMILES	CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl.Cl
PubChem CID	64713

Physical properties
Physical form	Powder
Appearance	Yellow crystalline powder,odorless (Results:Conforms)
H-bond donors / acceptors	2 / 2
TPSA	6.5 Å²
Synonyms	Meclozine dihydrochloride, 1-(p-chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)piperazine Dihydrochloride, Meclizine dihydrochloride, 1-((4-Chlorophenyl)(phenyl)methyl)-4-(3-methylbenzyl)piperazine dihydrochloride, Meclizine 2HCl, Vertizine, Ancolan dihydrochloride, V-Cline, Meclizine hydrochloride anhydrous, Postafene dihydrochloride, 1-[(4-chlorophenyl)(phenyl)methyl]-4-[(3-methylphenyl)methyl]piperazine dihydrochloride, Meclizine (dihydrochloride)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 1104-22-9

Reference Standard

Meclizine Dihydrochloride

CAS: 1104-22-9
Formula: C₂₅H₂₉Cl₃N₂
MW: 463.9 g/mol

In stock

Frequently asked questions

What is the CAS number of Meclizine HCl?

The CAS Registry Number of Meclizine HCl is 1104-22-9. It is also known as Meclozine dihydrochloride, 1-(p-chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)piperazine Dihydrochloride, Meclizine dihydrochloride.

What is the molecular formula and molecular weight of Meclizine HCl?

Meclizine HCl has the molecular formula C25H29Cl3N2 and a molecular weight of 463.9 g/mol.

What is Meclizine HCl used for?

Meclizine HCl is supplied as a characterised reference material related to Meclizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Meclizine HCl can I order?

We supply Meclizine HCl in IP/BP/USP (≥98.0%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Meclizine HCl?

Yes. Every lot of Meclizine HCl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Meclizine HCl be shipped internationally?

Yes. Meclizine HCl is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.